3-Hydroxy-3-[2-hydroxy-6-methyl-5-(2-methylpropyl)oxan-2-yl]butan-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 3-Hydroxy-3-[2-hydroxy-6-methyl-5-(2-methylpropyl)oxan-2-yl]butan-2-one
• 英文别名: 3-hydroxy-3-[2-hydroxy-6-methyl-5-(2-methylpropyl)oxan-2-yl]butan-2-one
• 化学式: C₁₄H₂₆O₄
• 分子量: 258.35
• InChiKey: GHKVVAMCGLYJLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] HEXADEPSIPEPTIDE ANALOGUES AS ANTICANCER COMPOUNDS<br/>[FR] ANALOGUES D'HEXADEPSIPEPTIDE EN TANT QUE COMPOSÉS ANTICANCÉREUX
  申请人：PIRAMAL ENTPR LTD

  公开号：WO2013168075A1

  公开（公告）日：2013-11-14

  This invention relates to an isolated compound of Formula (1) or derivatives or pharmaceutically acceptable salts thereof. The invention also includes all isomeric and tautomeric forms of the compound of Formula (1) or the derivatives thereof. The present invention further relates to processes for the production of the compound of Formula (1) by fermentation of the fungal strain of Actinomycetes (PM0895172/MTCC 684), pharmaceutical compositions comprising the compound of Formula (1) as the active ingredient; and use of the said compounds or composition containing them in the treatment of cancer.