3-ethyl-1H-pyrido[4,3-d]pyrimidine-2,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶并嘧啶类
• 英文名称: 3-ethyl-1H-pyrido[4,3-d]pyrimidine-2,4-dione
• 化学式: C₉H₉N₃O₂
• 分子量: 191.19
• InChiKey: MDQMMQKHLFFMHG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  62.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• 3-HETEROCYCLIC SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF USE THEREOF
  申请人：Merck Sharp & Dohme Corp.

  公开号：EP2222660B1

  公开（公告）日：2014-03-26
• QUINOLINE DERIVATIVES AS ALPHA4BETA7 INTEGRIN INHIBITORS
  申请人：Gilead Sciences, Inc.

  公开号：US20220119383A1

  公开（公告）日：2022-04-21

  The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.