1-(Pyrimidin-5-ylmethyl)-3-[3-(trifluoromethyl)phenyl]pyrido[1,2-a]pyrimidin-5-ium-2,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶并嘧啶类
• 英文名称: 1-(Pyrimidin-5-ylmethyl)-3-[3-(trifluoromethyl)phenyl]pyrido[1,2-a]pyrimidin-5-ium-2,4-dione
• 英文别名: 1-(pyrimidin-5-ylmethyl)-3-[3-(trifluoromethyl)phenyl]pyrido[1,2-a]pyrimidin-5-ium-2,4-dione
• 化学式: C20H14F3N4O2+
• 分子量: 399.3
• InChiKey: JGQOGAPDIYONKL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  67
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• [EN] META-DIAMIDE INSECTICIDES<br/>[FR] INSECTICIDES À BASE DE MÉTA-DIAMIDE
  申请人：FMC CORP

  公开号：WO2021055905A1

  公开（公告）日：2021-03-25

  Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein Q, Y, R1a, R1b, Z, W, R2, R3, R4, m, R5a and R5b are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  公开的是Formula 1的化合物，包括所有的几何和立体异构体，N-氧化物以及其盐，其中Q、Y、R1a、R1b、Z、W、R2、R3、R4、m、R5a和R5b的定义如披露所述。还公开了含有Formula 1化合物的组合物，以及用于控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与本发明的化合物或组合物的生物有效量接触。
• [EN] HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES<br/>[FR] PESTICIDES À BASE D'AZOLE BICYCLIQUE SUBSTITUÉ PAR HÉTÉROCYCLE
  申请人：DU PONT

  公开号：WO2016144351A1

  公开（公告）日：2016-09-15

  Disclosed are compounds of Formula (I), including all geometric and stereoisomers, N-oxides, and salts thereof, Formula (I) wherein Q is Formula (I) and A, R1, m, X1, X2, X3, X4, Y1, Y2 and Y3 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (I) and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  揭示了式（I）的化合物，包括所有的立体异构体、N-氧化物和盐，式（I）中Q为式（I），A、R1、m、X1、X2、X3、X4、Y1、Y2和Y3如披露中所定义。还披露了含有式（I）化合物的组合物，以及控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与本发明的化合物或组合物的生物有效量接触。
• [EN] PROCESS FOR THE PREPARATION OF N-[(5-PYRIMIDINYL)METHYL]-2-PYRIDINAMINES<br/>[FR] PROCÉDÉ DE PRÉPARATION DE N-[(5-PYRIMIDINYL)MÉTHYL]-2-PYRIDINAMINES
  申请人：DU PONT

  公开号：WO2017189339A1

  公开（公告）日：2017-11-02

  Disclosed is a method for preparing a compound of Formula (1) wherein R1 is H or C1-C3 alkyl, and the use of a compound of Formula (1) in a method for preparing mesoionic compounds, comprising: (A) contacting a compound of Formula (2) with 2-aminopyridine (3) in the presence of an inert solvent, optionally in the presence of an acid catalyst, to form a compound of Formula (4) (Β) contacting the compound of Formula (4) with an alcohol R2OH to form a compound of Formula (5) in the presence of an inert solvent wherein R2 is C1-C4 alkyl; and (C) contacting the compound of Formula (5) with a borohydride reducing agent in the presence of an inert solvent to form a reaction mixture comprising the compound of Formula (1).

  揭示了一种制备化合物的方法，该化合物的化学式为(1)，其中R1为H或C1-C3烷基，并且使用化合物的方法的化学式(1)来制备中间离子化合物，包括：(A)在惰性溶剂的存在下，可选地在酸催化剂的存在下，将化学式(2)的化合物与2-氨基吡啶(3)接触，形成化学式(4)的化合物；(B)在惰性溶剂的存在下，将化学式(4)的化合物与醇R2OH接触，形成化学式(5)的化合物，其中R2为C1-C4烷基；以及(C)在惰性溶剂的存在下，将化学式(5)的化合物与硼氢化物还原剂接触，形成包含化学式(1)的反应混合物。
• [EN] PYRIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS<br/>[FR] COMPOSÉS DE PYRIDINE POUR LUTTER CONTRE DES NUISIBLES INVERTÉBRÉS
  申请人：FMC CORP

  公开号：WO2021155106A1

  公开（公告）日：2021-08-05

  Disclosed are compounds of Formula (1), including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, A, R2, R4, R5 and Q are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula (1) and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the disclosure.

  本文披露了Formula (1)的化合物，包括所有几何和立体异构体、N-氧化物和盐，其中R1、A、R2、R4、R5和Q如披露中所定义。还披露了含有Formula (1)化合物的组合物以及用于控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与本披露的化合物或组合物的生物有效量接触。
• [EN] ISOXAZOLINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS<br/>[FR] COMPOSÉS D'ISOXAZOLINE DESTINÉS À LA LUTTE CONTRE LES RAVAGEURS INVERTÉBRÉS
  申请人：FMC CORP

  公开号：WO2020018610A1

  公开（公告）日：2020-01-23

  Disclosed are Compounds of Formula (1) or (1'), wherein Q is (Q-1) or (Q-2); and R1, R2, R3, J and X are as defined in the disclosure. Also disclosed are compositions containing the Compounds of Formula (1) or Formula (1') and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a Compound or a composition of the invention.

  揭示了式（1）或（1'）的化合物，其中Q为（Q-1）或（Q-2）；R1、R2、R3、J和X的定义如披露所述。还披露了含有式（1）或式（1'）化合物的组合物，以及用于控制无脊椎动物害虫的方法，包括将无脊椎动物害虫或其环境与本发明中的化合物或组合物的生物有效量接触。