3-(3-nitrophenyl)-2-phenylacrylonitrile | 62297-46-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 3-(3-nitrophenyl)-2-phenylacrylonitrile
• 英文别名: trans-α-3-Nitrophenyl-β-phenyl-acrylnitril；3c-(3-nitro-phenyl)-2-phenyl-acrylonitrile；(Z)-3-(3-nitrophenyl)-2-phenylprop-2-enenitrile
• CAS: 62297-46-5
• 化学式: C₁₅H₁₀N₂O₂
• 分子量: 250.257
• InChiKey: MHBAKHXIYJYROG-NTEUORMPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  69.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-(3-nitrophenyl)-2-phenylacrylonitrile 在 溶剂黄146 、 锌 作用下， 以48%的产率得到3-(3-aminophenyl)-2-phenylacrylonitrile
  参考文献：
  名称：

  Selective fluorescence sensing of cyanide with an o-(carboxamido)trifluoroacetophenone fused with a cyano-1,2-diphenylethylene fluorophore

  摘要：

  A novel fluorescence probe has been synthesized, which consists of o-(carboxamido)trifluoroacetophenone moiety as the recognition element and cyano-1,2-diphenylethylene moiety as the signaling unit. Fluorescence titrations of the probe with anions such as F-, Cl-, I-, CN-, SCN-, AcO-, H2PO4-, HSO4-, and ClO4- as their BU4N+ salts in acetonitrile show that CN- is the most efficient quencher, AcO- and F- follow it, and other anions show little changes. In an aqueous medium, MeOH-water (9:1), the probe shows fluorescence quenching only toward cyanide and no changes toward the other anions. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.07.065
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氯化亚砜 作用下， 生成 3-(3-nitrophenyl)-2-phenylacrylonitrile
  参考文献：
  名称：

  Pfeiffer; Engelhardt; Alfuss, Justus Liebigs Annalen der Chemie, 1928, vol. 467, p. 171

  摘要：

  DOI：

文献信息

• Brand; Loehr, Journal fur praktische Chemie (Leipzig 1954), 1925, vol. <2> 109, p. 375
  作者：Brand、Loehr

  DOI：——

  日期：——
• Pfeiffer; Engelhardt; Alfuss, Justus Liebigs Annalen der Chemie, 1928, vol. 467, p. 171
  作者：Pfeiffer、Engelhardt、Alfuss

  DOI：——

  日期：——
• Selective fluorescence sensing of cyanide with an o-(carboxamido)trifluoroacetophenone fused with a cyano-1,2-diphenylethylene fluorophore
  作者：Hanna Lee、Yun Mi Chung、Kyo Han Ahn

  DOI：10.1016/j.tetlet.2008.07.065

  日期：2008.9

  A novel fluorescence probe has been synthesized, which consists of o-(carboxamido)trifluoroacetophenone moiety as the recognition element and cyano-1,2-diphenylethylene moiety as the signaling unit. Fluorescence titrations of the probe with anions such as F-, Cl-, I-, CN-, SCN-, AcO-, H2PO4-, HSO4-, and ClO4- as their BU4N+ salts in acetonitrile show that CN- is the most efficient quencher, AcO- and F- follow it, and other anions show little changes. In an aqueous medium, MeOH-water (9:1), the probe shows fluorescence quenching only toward cyanide and no changes toward the other anions. (C) 2008 Elsevier Ltd. All rights reserved.