(cyclohexylamino) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyldec-9-enoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: (cyclohexylamino) (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methyldec-9-enoate
• 化学式: C₃₂H₄₂N₂O₄
• 分子量: 518.7
• InChiKey: MRSGZODQPYDXMU-JGCGQSQUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.8
• 重原子数：
  38
• 可旋转键数：
  15
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF
  申请人：Aileron Therapeutics, Inc.

  公开号：US20170066714A1

  公开（公告）日：2017-03-09

  Provided are crystalline α, α-disubstituted amino acids and their crystalline salts containing a terminal alkene on one of their side chains, as well as optionally crystalline halogenated and deuterated analogs of the α, α-disubstituted amino acids and their salts; methods of making these, and methods of using these.
• US9845287B2
  申请人：——

  公开号：US9845287B2

  公开（公告）日：2017-12-19
• [EN] DISUBSTITUTED AMINO ACIDS AND METHODS OF PREPARATION AND USE THEREOF<br/>[FR] ACIDES AMINÉS DISUBSTITUÉS ET PROCÉDÉS DE PRÉPARATION ET D'UTILISATION DE CEUX-CI
  申请人：AILERON THERAPEUTICS INC

  公开号：WO2014071241A1

  公开（公告）日：2014-05-08

  Provided are crystalline α, α-disubstituted amino acids and their crystalline salts containing a terminal alkene on one of their side chains, as well as optionally crystalline halogenated and deuterated analogs of the a, a-disubstituted amino acids and their salts; methods of making these, and methods of using these.