(1S,2R,6S,16E,18E,20R,21S)-11-chloro-6,21-dihydroxy-20-methoxy-2,5,9,12,16-pentamethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaene-8,23-dione

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酰胺类
• 英文名称: (1S,2R,6S,16E,18E,20R,21S)-11-chloro-6,21-dihydroxy-20-methoxy-2,5,9,12,16-pentamethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaene-8,23-dione
• 化学式: C₂₈H₃₇ClN₂O₇
• 分子量: 549.1
• InChiKey: HJVXPWHPKAVNLS-GRMOEYBASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  38
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  121
• 氢给体数：
  3
• 氢受体数：
  7

文献信息

• HYDRAZINYL-INDOLE COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE
  申请人：REDWOOD BIOSCIENCE, INC.

  公开号：US20140141025A1

  公开（公告）日：2014-05-22

  The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.

  本公开提供了用于生产这些共轭物的共轭结构（例如，多肽共轭物）和肼基吲哚化合物。该公开还提供了生产这种共轭物的方法，以及使用这些共轭物的方法。
• Hydrazinyl-Indole Compounds and Methods for Producing a Conjugate
  申请人：Redwood Bioscience, Inc.

  公开号：US20180104351A1

  公开（公告）日：2018-04-19

  The present disclosure provides conjugate structures (e.g., polypeptide conjugates) and hydrazinyl-indole compounds used to produce these conjugates. The disclosure also provides methods of production of such conjugates, as well as methods of using the same.
• US9310374B2
  申请人：——

  公开号：US9310374B2

  公开（公告）日：2016-04-12