4-amino-2-tert-butyl-2,3-dihydro-1H-isoindol-1-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 4-amino-2-tert-butyl-2,3-dihydro-1H-isoindol-1-one
• 英文别名: 4-amino-2-tert-butyl-3H-isoindol-1-one
• 化学式: C₁₂H₁₆N₂O
• 分子量: 204.27
• InChiKey: WYYHSHNASPPXAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  46.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Compositions comprising anti-CD38 antibodies and lenalidomide
  申请人：SANOFI

  公开号：US10342869B2

  公开（公告）日：2019-07-09

  Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and lenalidomide compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.

  本文公开了包含抗 CD38 抗体和来那度胺化合物的组合物和试剂盒。还公开了用这些组合物和试剂盒治疗癌症（如多发性骨髓瘤）的方法。
• Compositions Comprising Anti-CD38 Antibodies and Lenalidomide
  申请人：The Regents of the University of California

  公开号：US20140161819A1

  公开（公告）日：2014-06-12

  Disclosed herein are compositions and kits which comprise anti-CD38 antibodies and lenalidomide compounds. Also disclosed are methods for treating cancers, such as multiple myeloma, in subjects with the compositions and kits.