(2S,3S)-1,4-bis[(t-butyldiphenylsilyl)oxy]-2,3-diazidobutane | 254101-58-1

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: (2S,3S)-1,4-bis[(t-butyldiphenylsilyl)oxy]-2,3-diazidobutane
• 英文别名: tert-butyl-[(2S,3S)-2,3-diazido-4-[tert-butyl(diphenyl)silyl]oxybutoxy]-diphenylsilane
• CAS: 254101-58-1
• 化学式: C₃₆H₄₄N₆O₂Si₂
• 分子量: 648.955
• InChiKey: AFRAUAZNUWOSLC-KKLWWLSJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  46
• 可旋转键数：
  15
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  47.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (2S,3S)-1,4-bis[(t-butyldiphenylsilyl)oxy]-2,3-diazidobutane 在 palladium on activated charcoal 氢气 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 20.0 ℃ 、101.33 kPa 条件下， 反应 22.5h， 生成 (2S,3S)-N,N'-di(p-bromobenzoyl)-1,4-bis[(t-butyldiphenylsilyl)oxy]-2,3-diaminobutane
  参考文献：
  名称：

  Syntheses of C2-symmetric vicinal diamines derived from tartaric acid

  摘要：

  C-2-symmetric vicinal diamines 3b-f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d-f were generated from dihydroxydiazide 7 via deprotection-reprotection strategies. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00353-5
• 作为产物：
  描述：

  叔丁基二苯基氯硅烷 、 (2R,3R)-2,3-diazidobutane-1,4-diol 在 咪唑 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以94%的产率得到(2S,3S)-1,4-bis[(t-butyldiphenylsilyl)oxy]-2,3-diazidobutane
  参考文献：
  名称：

  Syntheses of C2-symmetric vicinal diamines derived from tartaric acid

  摘要：

  C-2-symmetric vicinal diamines 3b-f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d-f were generated from dihydroxydiazide 7 via deprotection-reprotection strategies. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00353-5

文献信息

• Syntheses of C2-symmetric vicinal diamines derived from tartaric acid
  作者：Andreas Scheurer、Paul Mosset、Rolf W. Saalfrank

  DOI：10.1016/s0957-4166(99)00353-5

  日期：1999.9

  C-2-symmetric vicinal diamines 3b-f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d-f were generated from dihydroxydiazide 7 via deprotection-reprotection strategies. (C) 1999 Elsevier Science Ltd. All rights reserved.