2,2,2-trichloroethyl N-[(2R,4S,5S)-6-(hydroxymethyl)-4,5-dimethyl-2-prop-2-enoxyoxan-3-yl]carbamate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2,2,2-trichloroethyl N-[(2R,4S,5S)-6-(hydroxymethyl)-4,5-dimethyl-2-prop-2-enoxyoxan-3-yl]carbamate
• 化学式: C₁₄H₂₂Cl₃NO₅
• 分子量: 390.7
• InChiKey: ZKLTYMIHCLUKAO-KCULMAPZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  77
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• Synthetic Oligosaccharides for Staphylococcus Vaccine
  申请人：CAMPBELL A. Stewart

  公开号：US20140170151A1

  公开（公告）日：2014-06-19

  The present invention synthetic oligo-β-(1→6)-glucosamine structures and a methodology which essentially allows for the synthesis of any oligo-β-(1→6)-glucosamine species having a definite number of monosaccharide units, including a set pattern of acetylated and non-acetylated residues. The invention further provides antibodies to these synthetic oligo-β-(1→6)-glucosamines as well as compositions thereof and methods for treating and preventing infections caused by bacteria expressing poly-β-(1→6)-glucosamines, such as Staphylococcus aureus.