N-[[2-(1-amino-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]methyl]-9,9-dimethyl-6-oxodecanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: N-[[2-(1-amino-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]methyl]-9,9-dimethyl-6-oxodecanamide
• 化学式: C₂₆H₃₄N₄O₆
• 分子量: 498.6
• InChiKey: ASIDDWYXDTWJPV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  36
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  147
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• 5-substituted isoindoline compounds
  申请人：CELGENE CORPORATION

  公开号：EP2749559A1

  公开（公告）日：2014-07-02

  The present invention relates to 5-substituted isoindoline compounds of formula (III) or formula (IV) wherein R10, R11, R13, R14, X and Y are as defined herein; or a pharmaceutically acceptable salt, solvate, stereoisomer, or prodrug thereof. The present invention also relates to a pharmaceutical composition of the compounds of the invention. The present invention also relates to a compound of the invention for use in treating, managing or preventing disease conditions as disclosed herein.

  本发明涉及式 (III) 的 5-取代异吲哚啉化合物 或式（IV） 其中R10、R11、R13、R14、X和Y如本文所定义；或其药学上可接受的盐、溶液、立体异构体或原药。本发明还涉及本发明化合物的药物组合物。本发明还涉及用于治疗、控制或预防本文所公开的疾病状况的本发明化合物。
• Organic Electroluminescent Element, Material for Organic Electroluminescent Element, Light Emitting Device, Display Device and Lighting Device Each Using Said Element, and Compound Used for Said Element
  申请人：Yamamoto Yosuke

  公开号：US20140319507A1

  公开（公告）日：2014-10-30

  This application relates, in part, to an organic electroluminescent element including a substrate, a pair of electrodes including an anode and a cathode, disposed on the substrate, and at least one organic layer including a light emitting layer, disposed between the electrodes, in which at least one layer of the organic layer(s) contains a compound represented by the following formula (1). The organic electroluminescent element has low driving voltage and excellent durability. wherein X 1 to X 11 represent CR 0 or N, and R 0 represents a hydrogen atom or a substituent. Adjacent two of X 1 to X 11 each independently represent at least CR 0 , R 0 s of the adjacent two CR 0 s are bonded to each other to form a ring, and only one R 0 of the adjacent two CR 0 s represents an aryl group or a heteroaryl group.