(6-amino-7H-purin-2-yl)phosphonic acid;pyridine-3-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: (6-amino-7H-purin-2-yl)phosphonic acid;pyridine-3-carboxamide
• 化学式: C11H12N7O4P
• 分子量: 337.23
• InChiKey: UHONOZSMOQXGGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.08
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  194
• 氢给体数：
  5
• 氢受体数：
  9

文献信息

• Production of oil in vegetative tissues
  申请人：Board of Trustees of Michigan State University

  公开号：US10006039B2

  公开（公告）日：2018-06-26

  The present invention relates to compositions and methods for providing RNA interference (RNAi) vectors comprising trigalactosyldiacylglycerol (tgd) biosynthesis enzyme constructs for increasing oil content of plants. Further, the use of tgd RNAi silencing vectors in combination with co-expression of heterologous oil regulating transcription factors, such as WRINKLED1, are contemplated to overcome the reduced growth and variable levels of embryonic lethality in plants with reduced TGD protein. Additionally, plants having reduced APS1, a gene encoding a major catalytic isoform of the small subunit of AGPase (AGP(−) plants), co-expressing a heterologous oil modulating transcription factor are contemplated for use in combination with plants having reduced TGD. Oil harvested from vegetative tissues of plants comprising vectors and genes of the present invention is contemplated for use in biofuel and biodiesel products.

  本发明涉及提供包含三聚半乳糖二乙酰甘油（tgd）生物合成酶构建体的 RNA 干扰（RNAi）载体以增加植物含油量的组合物和方法。此外，还考虑将 tgd RNAi 沉默载体与异源油脂调节转录因子（如 WRINKLED1）的共同表达结合使用，以克服 TGD 蛋白减少的植物的生长减弱和不同程度的胚胎致死率。此外，还考虑将编码 AGP 酶小亚基主要催化异构体的 APS1 基因（AGP(-)植物）表达量减少的植物与异源油脂调节转录因子结合起来，与 TGD 蛋白减少的植物一起使用。从含有本发明载体和基因的植物的无性组织中提取的油可用于生物燃料和生物柴油产品。
• PRODUCTION OF OIL IN VEGETATIVE TISSUES
  申请人：BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY

  公开号：US20140228585A1

  公开（公告）日：2014-08-14

  The present invention relates to compositions and methods for providing RNA interference (RNAi) vectors comprising trigalactosyldiacylglycerol (tgd) biosynthesis enzyme constructs for increasing oil content of plants. Further, the use of tgd RNAi silencing vectors in combination with co-expression of heterologous oil regulating transcription factors, such as WRINKLED1, are contemplated to overcome the reduced growth and variable levels of embryonic lethality in plants with reduced TGD protein. Additionally, plants having reduced APS1, a gene encoding a major catalytic isoform of the small subunit of AGPase (AGP(−) plants), co-expressing a heterologous oil modulating transcription factor are contemplated for use in combination with plants having reduced TGD. Oil harvested from vegetative tissues of plants comprising vectors and genes of the present invention is contemplated for use in biofuel and biodiesel products.