3-ethyl-6-methyl-9,9a-dihydro-4aH-thioxanthene 10,10-dioxide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻喃类
• 英文名称: 3-ethyl-6-methyl-9,9a-dihydro-4aH-thioxanthene 10,10-dioxide
• 化学式: C₁₆H₁₈O₂S
• 分子量: 274.4
• InChiKey: DCBFPWUIIHIRHI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• ANTI-MALARIAL COMPOUNDS
  申请人：Cellceutix Corporation

  公开号：US20150072997A1

  公开（公告）日：2015-03-12

  The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.

  本发明提供了三环化合物、芳香酰胺化合物和其他化合物，以及包含它们的组合物，用于治疗疟疾，并且包括将这些化合物用于动物治疗疟疾的方法。
• COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS
  申请人：Cellceutix Corporation

  公开号：US20140364364A1

  公开（公告）日：2014-12-11

  The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.
• COMPOUNDS AND METHODS FOR TREATING MALARIA
  申请人：Cellceutix Corporation

  公开号：US20150094294A1

  公开（公告）日：2015-04-02

  The present disclosure provides compounds, specifically pyrimidin-4,6-dicarboxylic acid amide derivatives, or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing said compounds. Also provided are methods for treating a mammal having malaria, or killing or inhibiting the growth of a Plasmodium species, comprising administering to said mammal or contacting said Plasmodium species with, an effective amount of a pyrimidin- 4,6 -dicarboxylic acid amide derivative.
• Compounds for use in Treatment of Mucostis
  申请人：Cellceutix Corporation

  公开号：US20160213668A1

  公开（公告）日：2016-07-28

  The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.
• Compounds For Use In Treatment Of Mucositis
  申请人：Cellceutix Corporation

  公开号：US20170224640A1

  公开（公告）日：2017-08-10

  The present invention provides methods for treating and/or preventing mucostitis with one or more compounds, or pharmaceutically acceptable salts thereof, disclosed herein, or compositions comprising the same.