furan;7H-purin-6-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: furan;7H-purin-6-amine
• 化学式: C9H9N5O
• 分子量: 203.2
• InChiKey: FZJDWSPZLBEMTG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.21
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  93.6
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• USE FOR DEOXYNUCLEOSIDE/NUCLEOSIDE COMBINATION IN PREPARATION OF TUMOR MEDICAMENT
  申请人：Zhang, Shizhuang

  公开号：EP2769727A1

  公开（公告）日：2014-08-27

  This invention is related to a use for a deoxynucleoside/nucleoside combination in the preparation of a medicament that fights tumors. Said deoxynucleoside comprises deoxyadenosine, deoxyguanosine, deoxycytidine, and thymidine; and said nucleoside comprises adenosine, guanosine, cytidine, uridine, deoxyadenosine, deoxyguanosine, deoxycytidine, and thymidine. The deoxynucleoside/nucleoside combination of the invention is used to prepare a medicament for many types of common malignant tumors, such as gastric cancer, lung cancer, liver cancer, colon cancer, breast cancer, and tumors of the reproductive system.

  本发明涉及一种脱氧核苷/核苷组合在制备抗肿瘤药物中的用途。所述脱氧核苷包括脱氧腺苷、脱氧鸟苷、脱氧胞苷和胸苷；所述核苷包括腺苷、鸟苷、胞苷、尿苷、脱氧腺苷、脱氧鸟苷、脱氧胞苷和胸苷。本发明的脱氧核苷/核苷组合可用于制备治疗多种常见恶性肿瘤的药物，如胃癌、肺癌、肝癌、结肠癌、乳腺癌和生殖系统肿瘤。
• DEOXYNUCLEOSIDE/NUCLEOSIDE COMBINATION FOR USE IN THE TREATMENT OF TUMORS
  申请人：Zhang, Shizhuang

  公开号：EP2769727B1

  公开（公告）日：2016-05-18