9H-fluoren-9-ylmethyl (3S)-7-amino-3-(methylamino)-2-oxoheptanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 9H-fluoren-9-ylmethyl (3S)-7-amino-3-(methylamino)-2-oxoheptanoate
• 化学式: C₂₂H₂₆N₂O₃
• 分子量: 366.5
• InChiKey: DMLNIKWORJACQV-FQEVSTJZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  27
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  81.4
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• SOLID PHASE PEPTIDE SYNTHESIS OF INSULIN USING SIDE CHAIN ACHORED LYSINE
  申请人：BARLOS Kleomenis K.

  公开号：US20160031962A1

  公开（公告）日：2016-02-04

  The present application discloses the preparation of peptides, including insulin and insulin derivatives, using efficient methods for solid-phase and solution phase peptide synthesis.

  本发明公开了使用固体相和溶液相肽合成的高效方法制备肽，包括胰岛素及其衍生物。
• PEPTIDE-DENDRIMER CONJUGATES AND USES THEREOF
  申请人：Angiochem Inc.

  公开号：US20160015823A1

  公开（公告）日：2016-01-21

  The invention relates to dendrimers conjugated to multiple targeting peptides and one or more therapeutic, diagnostic, or imaging agents for delivery of such agents across the blood-brain barrier and into certain cell types including, cells expressing the LRP-1 receptor. Also described are methods of making compounds that comprise dendrimers conjugated to targeting peptides and therapeutic, diagnostic, or imaging agents.

  本发明涉及树状分子与多个靶向肽以及一个或多个治疗、诊断或成像剂的共轭，用于将这些剂送达血脑屏障并进入特定细胞类型，包括表达LRP-1受体的细胞。还描述了制备包含树状分子与靶向肽和治疗、诊断或成像剂的化合物的方法。
• CONFORMATIONS OF DIVERGENT PEPTIDES WITH MINERAL BINDING AFFINITY
  申请人：KAOHSIUNG MEDICAL UNIVERSITY

  公开号：US20150320876A1

  公开（公告）日：2015-11-12

  A series of peptides with divergent confirmations including structures of formula (1A), (1B), (2) and (3) are provided. In the formula, wherein U, G, A, B, R1, R2 and T are as defined in the specification. The divergent peptides disclosed in the present invention are characterized in a mineral binding affinity function.

  提供了一系列具有不同构象的肽，包括公式（1A），（1B），（2）和（3）的结构。在公式中，其中U，G，A，B，R1，R2和T的定义如规范中所定义。本发明披露的不同肽具有矿物结合亲和力功能的特征。
• IMMOBILIZATION OF ANTIMICROBIAL POLYMERS ON RO MEMBRANE TO REDUCE BIOFILM GROWTH AND BIOFOULING
  申请人：Kasher Ron

  公开号：US20140238939A1

  公开（公告）日：2014-08-28

  The present invention discloses antimicrobial water treatment membranes, comprising a water treatment membrane, covalently attached to one or more antimicrobial polymers or derivatives thereof, either directly or via one or more tether molecules. There are also provided a process for preparing these antimicrobial membranes, and uses thereof in water treatment applications.
• US8889828B2
  申请人：——

  公开号：US8889828B2

  公开（公告）日：2014-11-18