3,4-dihydro-6-methyl-3-m-tolyl-2H-benzo[e][1,3]oxazine | 1217300-38-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 3,4-dihydro-6-methyl-3-m-tolyl-2H-benzo[e][1,3]oxazine
• 英文别名: 6-Methyl-3-(3-methylphenyl)-2,4-dihydro-1,3-benzoxazine
• CAS: 1217300-38-3
• 化学式: C₁₆H₁₇NO
• 分子量: 239.317
• InChiKey: WCNNTYQPMCVMRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 对甲酚 、 3-甲基苯胺 反应 0.05h， 以72%的产率得到3,4-dihydro-6-methyl-3-m-tolyl-2H-benzo[e][1,3]oxazine
  参考文献：
  名称：

  在热和微波条件下一锅合成[1,3]-恶嗪和[1,3]-噻嗪衍生物

  摘要：

  据报道，在常规加热以及微波辐射下，可以简单有效地合成取代的苯并[1,3]恶嗪和苯并[1,3]噻嗪衍生物。该化合物是通过使富电子的酚，甲醛和芳族胺在甲醇中反应而获得的。在常规加热下耗时12–16 hr的反应在微波辐射（无溶剂）下在几分钟内成功完成，收率中等至极佳。J.杂环化​​学.2010。

  DOI：

  10.1002/jhet.280

文献信息

• BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME
  申请人：Cytec Technology Corp.

  公开号：EP2831052B1

  公开（公告）日：2017-06-14
• Benzoxazines and Compositions Containing the Same
  申请人：CYTEC TECHNOLOGY CORP.

  公开号：US20130267659A1

  公开（公告）日：2013-10-10

  Disclosed herein are monofunctional benzoxazine compounds having at least one electron-withdrawing group. The monofunctional benzoxazine compounds may be combined with one or more multifunctional benzoxazine compounds to form a unique benzoxazine blend. This benzoxazine blend may be combined with additional components such as catalysts and toughening agents to form a curable resin composition suitable for forming resinous films or composite materials. The presence of monofunctional benzoxazine improves the processability of the benzoxazine-based resin composition by reducing the viscosity of the resin composition, and results in improved tack and drape in the films and composite materials formed from the composition without the loss of modulus in the cured resin.
• US9499666B2
  申请人：——

  公开号：US9499666B2

  公开（公告）日：2016-11-22
• One pot synthesis of [1,3]-oxazine and [1,3]-thiazine derivatives under thermal and microwave conditions
  作者：S. Tumtin、I. T. Phucho、A. Nongpiur、R. Nongrum、J. N. Vishwakarma、B. Myrboh、R. L. Nongkhlaw

  DOI：10.1002/jhet.280

  日期：——

  efficient synthesis of substituted benzo [1,3] oxazine and benzo [1,3] thiazine derivatives under conventional heating, as well as microwave irradiation is reported. The compounds were obtained by the reaction of electron rich phenols, formaldehyde, and aromatic amines in methanol. Reactions which take 12–16 hr under conventional heating were successfully completed within a few minutes under microwave irradiation

  据报道，在常规加热以及微波辐射下，可以简单有效地合成取代的苯并[1,3]恶嗪和苯并[1,3]噻嗪衍生物。该化合物是通过使富电子的酚，甲醛和芳族胺在甲醇中反应而获得的。在常规加热下耗时12–16 hr的反应在微波辐射（无溶剂）下在几分钟内成功完成，收率中等至极佳。J.杂环化​​学.2010。