1-[6-[2-[[3-[2-azido-2-[2-[2-[3-[1-[4-(azidomethoxy)-5-[(phosphanylidyne-lambda5-phosphanylidene)phosphanyloxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-2-oxoethoxy]ethoxy]ethoxy]benzoyl]amino]ethylamino]-6-oxohexyl]-3,3-dimethyl-2-[(E,3E)-3-[3-methyl-1-phenyl-3-(5-sulfopentyl)indol-2-ylidene]prop-1-enyl]indol-1-ium-5-sulfonic acid

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 英文名称: 1-[6-[2-[[3-[2-azido-2-[2-[2-[3-[1-[4-(azidomethoxy)-5-[(phosphanylidyne-lambda5-phosphanylidene)phosphanyloxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-2-oxoethoxy]ethoxy]ethoxy]benzoyl]amino]ethylamino]-6-oxohexyl]-3,3-dimethyl-2-[(E,3E)-3-[3-methyl-1-phenyl-3-(5-sulfopentyl)indol-2-ylidene]prop-1-enyl]indol-1-ium-5-sulfonic acid
• 英文别名: 1-[6-[2-[[3-[2-azido-2-[2-[2-[3-[1-[4-(azidomethoxy)-5-[(phosphanylidyne-λ5-phosphanylidene)phosphanyloxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-2-oxoethoxy]ethoxy]ethoxy]benzoyl]amino]ethylamino]-6-oxohexyl]-3,3-dimethyl-2-[(E,3E)-3-[3-methyl-1-phenyl-3-(5-sulfopentyl)indol-2-ylidene]prop-1-enyl]indol-1-ium-5-sulfonic acid
• 化学式: C67H79N13O17P3S2+
• 分子量: 1495.5
• InChiKey: RFFVXEZXLNKDEI-UHFFFAOYSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  102
• 可旋转键数：
  39
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  353
• 氢给体数：
  6
• 氢受体数：
  22

文献信息

• [EN] POLYMETHINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS<br/>[FR] COMPOSÉS DE POLYMÉTHINE ET LEUR UTILISATION COMME MARQUEURS FLUORESCENTS
  申请人：ILLUMINA CAMBRIDGE LTD

  公开号：WO2014135221A1

  公开（公告）日：2014-09-12

  The present disclosure relates to new polymethine compounds and their use as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.

  本公开涉及新的聚甲亚胺化合物及其作为荧光标记物的用途。这些化合物可用作核酸测序应用中核苷酸的荧光标记物。