tert-butyl 2-(9H-fluoren-1-yl)-2-formyloxyacetate

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: tert-butyl 2-(9H-fluoren-1-yl)-2-formyloxyacetate
• 化学式: C₂₀H₂₀O₄
• 分子量: 324.4
• InChiKey: BKKPDEKBVUCSLX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• SOLID PHASE PEPTIDE SYNTHESIS PROCESSES AND ASSOCIATED SYSTEMS
  申请人：Massachusetts Institute of Technology

  公开号：EP2970374A2

  公开（公告）日：2016-01-20
• SOLID PHASE PEPTIDE SYNTHESIS
  申请人：Massachusetts Institute of Technology

  公开号：EP2970374B1

  公开（公告）日：2019-11-06
• [EN] SOLID PHASE PEPTIDE SYNTHESIS PROCESSES AND ASSOCIATED SYSTEMS<br/>[FR] MÉTHODES DE SYNTHÈSE DE PEPTIDE EN PHASE SOLIDE ET SYSTÈMES ASSOCIÉS
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2014149387A2

  公开（公告）日：2014-09-25

  Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that have been immobilized on a solid support. In certain embodiments, the inventive systems and methods can be used to perform solid phase peptide synthesis quickly while maintaining high yields. Certain embodiments relate to processes and systems that may be used to heat, transport, and/or mix reagents in ways that reduce the amount of time required to perform solid phase peptide synthesis.