7-methoxy-1-methyl-9-[2-(1H-1,2,4-triazol-5-yl)ethyl]pyrido[3,4-b]indole

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 哈马拉生物碱
• 英文名称: 7-methoxy-1-methyl-9-[2-(1H-1,2,4-triazol-5-yl)ethyl]pyrido[3,4-b]indole
• 化学式: C₁₇H₁₇N₅O
• 分子量: 307.35
• InChiKey: BGLGUULRIOHOML-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  68.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH
  申请人：Osteoqc Inc.

  公开号：EP2968284A2

  公开（公告）日：2016-01-20
• [EN] ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH<br/>[FR] DÉRIVÉS D'ALKYL-AMINE HARMINE POUR FAVORISER LA CROISSANCE OSSEUSE
  申请人：OSSIFI INC

  公开号：WO2014153203A2

  公开（公告）日：2014-09-25

  In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I, Formula II, or Formula III. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease and cancer, using a compound of Formula I, Formula II, or Formula III.