N,N-dimethyl-1-phenothiazin-10-ylpropan-1-amine | 101976-40-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: N,N-dimethyl-1-phenothiazin-10-ylpropan-1-amine
• CAS: 101976-40-3
• 化学式: C₁₇H₂₀N₂S
• 分子量: 284.4
• InChiKey: WNJQAWAODSSBNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  31.8
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• TREATMENT OF PROTEIN AGGREGATION DISEASES
  申请人：Wilson Stuart Mark

  公开号：US20100035859A1

  公开（公告）日：2010-02-11

  A method of treatment for the prevention or therapy of a protein aggregation disease includes the administration in combination of a first active medicament and a second active medicament, wherein the first active medicament is active to impede aggregation of amyloid protein and the second active medicament is active to disaggregate previously formed aggregates of amyloid protein.