2,3-dimethoxy-4-methylphenol | 6375-85-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2,3-dimethoxy-4-methylphenol
• CAS: 6375-85-5
• 化学式: C₉H₁₂O₃
• 分子量: 168.192
• InChiKey: PZHLHCXQYZCQCF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  38.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,3-dimethoxy-4-methylphenol 在 RuZn₂In₂S₅ 作用下， 以 乙腈 为溶剂， 反应 96.0h， 以89%的产率得到4,4'5,5'-tetramethoxy-6,6'-dimethyl-[1,1'-biphenyl]-3,3'-diol
  参考文献：
  名称：

  一种甲酚制备联苯二酚的方法

  摘要：

  本发明涉及一种甲酚类化合物制备联苯二酚的方法。该方法以光能为能量，在半导体光催化剂的催化作用下，即可将甲酚转化为联苯二酚。其反应过程如下：将甲酚，半导体光催化剂和溶剂混合后，加入到耐压石英容器(>1MPa)中并用惰性气体置换。常温光照搅拌，反应时间大于或等于1小时。反应结束后催化剂与反应体系通过过滤分离，并可多次循环使用。反应产物通过结晶分离，联苯二酚的选择性可达61％。该方法制备的联苯二酚化合物可作为抗氧化剂及替代双酚A制备聚碳酸酯。

  公开号：

  CN114181047A
• 作为产物：
  描述：

  2,3-二甲氧基甲苯 、 甲酸 、 双氧水 以5%的产率得到
  参考文献：
  名称：

  ORITA, HIDEO;SHIMIZU, MASAO;HAYAKAWA, TAKASHI;TAKEHIRA, KATSUOMI, BULL. CHEM. SOC. JAP., 62,(1989) N, C. 1652-1657

  摘要：

  DOI：

文献信息

• Oxidation of Methoxy- and/or Methyl-Substituted Benzenes and Naphthalenes to Quinones and Phenols by H₂O₂in HCOOH
  作者：Hideo Orita、Masao Shimizu、Takashi Hayakawa、Katsuomi Takehira

  DOI：10.1246/bcsj.62.1652

  日期：1989.5

  The oxidation of a number of arenes (methoxybenzenes, methylbenzenes, and naphthalenes) to quinones and phenols by H2O2 in HCOOH has been examined. Methoxybenzenes were much more easily oxidized to p-benzoquinones than methylbenzenes (e.g., 1,3,5-trimethoxybenzene was oxidized to 2,6-dimethoxy-p-benzoquinone in a 75% yield and 1,2,4-trimethylbenzene to 2,3,5-trimethyl-p-benzoquinone in a 16% yield)

  已经研究了在 HCOOH 中通过 H2O2 将许多芳烃（甲氧基苯、甲苯和萘）氧化为醌和苯酚。甲氧基苯比甲基苯更容易氧化成对苯醌（例如，1,3,5-三甲氧基苯以 75% 的产率氧化成 2,6-二甲氧基-对苯醌，1,2,4-三甲苯氧化成 2， 3,5-三甲基-对苯醌，产率为 16%）。吸电子取代基，如硝基、氰基和氯基团，降低了反应物的转化率，并将产物的选择性从醌类变为酚类。甲氧基苄腈以中等产率氧化成相应的酚类（例如，2,6-二甲氧基苄腈以39%的产率和64%的选择性氧化成3-羟基-2,6-二甲氧基苄腈）。
• Stereoelectronic Effects on ¹H Nuclear Magnetic Resonance Chemical Shifts in Methoxybenzenes
  作者：Maja Lambert、Lars Olsen、Jerzy W. Jaroszewski

  DOI：10.1021/jo061757x

  日期：2006.12.1

  polyphenols due to hydrogen bonding and conjugative stabilization, the steric congestion in ortho-disubstituted anisoles outweighs the conjugative effects and forces the Ar−OCH3 torsion out of the ring plane, resulting in large stereoelectronic effects on the chemical shift of Hpara. Conformational searches and geometry optimizations for 3−16 at the B3LYP/6-31G** level, followed by B3LYP/6-311++G(2d

  1,2,3-苯三酚和4-甲基-1,2,3-苯三酚（各O-甲基醚的调查3 - 16）由1 H NMR光谱和密度泛函计算公开于实际有用的构象的影响1个ħ NMR化学位移在芳环上。虽然苯酚（2）向苯甲醚（1）的转化仅引起1 H NMR化学位移的小幅正变化（Δδ<0.08 ppm），并以H ortho > H meta > H para的顺序降低，但实验性的O-甲基化诱导了H para时，邻二取代苯酚的位移最大，Δδ= 0.19±0.02 ppm（n = 11）。差异是由于OH和OCH 3基团的构象行为不同所致。虽然邻二取代的OH基团由于氢键和共轭稳定作用而在多酚中保持平面状态，但邻二取代的各向异性空间中的空间拥挤超过了共轭效应，迫使Ar-OCH 3扭转出环平面，从而产生了较大的立体电子效应关于H para的化学位移。在B3LYP / 6-31G **级别对3 − 16进行构象搜索和几何优化，然后对所有低能构象体进行B3LYP
• DAMPING MATERIAL COMPOSITIONS AND DAMPING MATERIALS
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0299086A1

  公开（公告）日：1989-01-18

  A first damping material composition comprises (a-1) an epoxy resin, (b) a curing agent, and (c-1) a liquid polymer having in one molecule on the average 1.6 or more of at least one functional group selected from among carboxyl, acid anhydride, amino, amido, and mercapto groups capable of reacting with epoxy groups of the epoxy resin and having a glass transition point of up to 0°C. A second damping material composition comprises (a-2) an epoxy resin of polyglycidyl ether with polyol or its polymer, (b) a curing agent, and (c-2) an aromatic hydrocarbon, a phenol or polymer containing at least one of them as main component and having a softening point of up to 25°C. A third damping material composition comprises (1) an epoxy resin obtained by adding (c-3) a cyclic ester to (a-3) a bisphenol type epoxy resin in a weight ratio of (c-3) to (a-3) of 20180 to 98/2, and (b) a curing agent. The equivalent ratio (b)/(I) of (I) said epoxy resin to (b) said curing agent is in the range of 0.6 to 1.4.

  第一种阻尼材料组合物包括(a-1)环氧树脂、(b)固化剂和(c-1)液态聚合物，该聚合物在一个分子中平均含有 1.6 个或更多的至少一个官能团，这些官能团选自羧基、酸酐、氨基、胺基和巯基，能与环氧树脂的环氧基团反应，且玻璃化转变点不超过 0℃。第二种阻尼材料组合物包括：(a-2) 聚缩水甘油醚环氧树脂与多元醇或其聚合物；(b) 固化剂；(c-2) 芳香族碳氢化合物、苯酚或至少含有其中一种作为主要成分的聚合物，其软化点最高可达 25°C。第三种阻尼材料组合物包括：(1) 一种环氧树脂，将 (c-3) 环酯加入到 (a-3) 双酚型环氧树脂中，(c-3) 与 (a-3) 的重量比为 20180 至 98/2；(b) 一种固化剂。(I)所述环氧树脂与(b)所述固化剂的当量比(b)/(I)在 0.6 至 1.4 之间。
• FRACTIONAL CATALYTIC PYROLYSIS OF BIOMASS
  申请人：Agblevor Foster A.

  公开号：US20090165378A1

  公开（公告）日：2009-07-02

  Methods for fractional catalytic pyrolysis which allow for conversion of biomass into a slate of desired products without the need for post-pyrolysis separation are described. The methods involve use of a fluid catalytic bed which is maintained at a suitable pyrolysis temperature. Biomass is added to the catalytic bed, preferably while entrained in a non-reactive gas such as nitrogen, causing the biomass to become pyrolyzed and forming the desired products in vapor and gas forms, allowing the desired products to be easily separated.
• [EN] PYROLYSIS METHOD FOR PLANT BIOMASS<br/>[FR] PROCÉDÉ DE PYROLYSE DE LA BIOMASSE VÉGÉTALE
  申请人：TOYOTA MOTOR CO LTD

  公开号：WO2012090369A1

  公开（公告）日：2012-07-05

  An object of the present invention is to provide a convenient method for extracting a useful organic compound from plant biomass. According to the present invention, a method for pyrolyzing plant biomass comprising a 1st heating step in which biomass is heated at a 1st heating temperature and a 2nd heating step in which either a gasified product or a biomass residue obtained in the 1st heating step is heated at a 2nd heating temperature higher than the 1st heating temperature is provided. The method of the present invention makes it possible to extract useful organic compounds such as phenols from plant biomass with heat treatment alone.