2,3,4,5-tetramethyl-tetrahydro-thiophene-1,1-dioxide | 17346-95-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 硫杂环戊烷
• 英文名称: 2,3,4,5-tetramethyl-tetrahydro-thiophene-1,1-dioxide
• 英文别名: 2,3,4,5-Tetramethyl-tetrahydro-thiophen-1,1-dioxid；2,3,4,5-tetramethyl-3-sulfolane；2,3,4,5-Tetramethylthiolane 1,1-dioxide
• CAS: 17346-95-1
• 化学式: C₈H₁₆O₂S
• 分子量: 176.28
• InChiKey: NPMWMASMLLLYFA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2,3,4,5-tetramethyl-2,5-dihydro-thiophene-1,1-dioxide 在 溶剂黄146 、 铂 作用下， 生成 2,3,4,5-tetramethyl-tetrahydro-thiophene-1,1-dioxide
  参考文献：
  名称：

  Backer; Bolt, Recueil des Travaux Chimiques des Pays-Bas, 1935, vol. 54, p. 538,540

  摘要：

  DOI：

文献信息

• GAMMA SECRETASE MODULATORS
  申请人：Huang Xianhai

  公开号：US20100137320A1

  公开（公告）日：2010-06-03

  This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).

  本发明提供了一种新型的化合物，它们是γ-分泌酶的调节剂。这些化合物的化学式如下：（见原文） 此外，本发明还揭示了调节γ-分泌酶活性的方法以及使用化合物（I）治疗阿尔茨海默病的方法。
• Process for separating acid-containing gas mixtures
  申请人：Solvay SA

  公开号：EP2705893A1

  公开（公告）日：2014-03-12

  A process for reversibly removing at least one acid from a gas mixture comprising at least one acid and at least one of a carbonyl dihalide, a phosphoryl trihalide, a phosphorous pentafluoride, and an acid halide is provided. The process comprises contacting the gas mixture with a solvent comprising a sulphone compound.

  提供了一种用于可逆地从气体混合物中去除至少一种酸的过程，该气体混合物包括至少一种酸和至少一种羰基二卤化物、磷酰三卤化物、五氟化磷和酸卤化物之一。该过程包括将气体混合物与包含磺酰化合物的溶剂接触。
• METHOD FOR MANUFACTURING SULFOLENE COMPOUND AND METHOD FOR MANUFACTURING SULFOLANE COMPOUND
  申请人：Sumitomo Seika Chemicals Co., Ltd.

  公开号：EP2368888B1

  公开（公告）日：2014-03-26
• SULFOLANE COMPOSITION
  申请人：Miyada Masayoshi

  公开号：US20140012018A1

  公开（公告）日：2014-01-09

  The present invention aims to provide, with combination of a sulfolane compound and an organic alkanolamine compound, a sulfolane composition which is not likely to cause odor, can suppress pyrolysis of the sulfolane compound with a reduced amount of additives, and can reduce generation of sulfur dioxide. The present invention relates to a sulfolane composition containing a sulfolane compound represented by formula (1) and an organic alkanolamine compound, wherein R 1 to R 6 each independently represent a hydrogen atom or a C 1-6 alkyl group.
• US3960684A
  申请人：——

  公开号：US3960684A

  公开（公告）日：1976-06-01