1-(9H-fluoren-9-yl)-4-(3-phenylprop-2-enyl)piperazine

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 1-(9H-fluoren-9-yl)-4-(3-phenylprop-2-enyl)piperazine
• 化学式: C₂₆H₂₆N₂
• 分子量: 366.5
• InChiKey: RDNHEFWZOKNXKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Methods to control infection using new generation small molecule growth inhibitors
  申请人：Ohio State Innovation Foundation

  公开号：US11478454B2

  公开（公告）日：2022-10-25

  Disclosed herein are methods of treating a subject with a bacterial infection, or preventing a bacterial infection, comprising administering to the subject an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. Also described are methods of inhibiting bacterial growth in a plant comprising contacting the plant with an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. The methods are effective against an array of bacterial pathogens in various animals and plants.

  本文公开了治疗细菌感染或预防细菌感染的方法，包括向受试者施用有效量的至少一种具有 SM1、SM3、SM4 或 SM5 式的化合物或其衍生物。 还描述了抑制植物中细菌生长的方法，包括用有效量的至少一种具有 SM1、SM3、SM4 或 SM5 式的化合物或其衍生物与植物接触。 这些方法对各种动物和植物中的一系列细菌病原体有效。
• METHODS TO CONTROL INFECTION USING NEW GENERATION SMALL MOLECULE GROWTH INHIBITORS
  申请人：Ohio State Innovation Foundation

  公开号：US20200405691A1

  公开（公告）日：2020-12-31

  Disclosed herein are methods of treating a subject with a bacterial infection, or preventing a bacterial infection, comprising administering to the subject an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. Also described are methods of inhibiting bacterial growth in a plant comprising contacting the plant with an effective amount of at least one compound, or a derivative thereof, having the formula of SM1, SM3, SM4, or SM5. The methods are effective against an array of bacterial pathogens in various animals and plants.