2-[[(2R)-2,3-di(tricosa-10,12-diynoyloxy)propoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: 2-[[(2R)-2,3-di(tricosa-10,12-diynoyloxy)propoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
• 化学式: C54H93NO8P+
• 分子量: 915.3
• InChiKey: IDBJTPGHAMAEMV-OIVUAWODSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  17.4
• 重原子数：
  64
• 可旋转键数：
  46
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  108
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• [EN] PERFLUOROCHEMICAL EMULSION WITH STABILIZED VESICLES
  申请人：ALPHA THERAPEUTIC CORPORATION

  公开号：WO1989008459A1

  公开（公告）日：1989-09-21

  (EN) A stable perfluorochemical emulsion is provided which comprises perfluorochemical particles in stabilized vesicles. The vesicles comprise a biocompatible polymer formed by coating the perfluorochemical particles with one or more phospholipid monomer(s) and polymerizing the monomer(s).(FR) On a mis au point une émulsion perfluorochimique stable comprenant des particules perfluorochimiques contenues dans des vésicules stabilisés. Lesdits vésicules comprennent un polymène biocompatible formé par enrobage des particules perfluorochimiques avec un ou plusieurs monomères phospholipidiques, puis par polymérisation des monomères.

  提供一种稳定的全氟化合物乳液，其中包含稳定的囊泡中的全氟化合物颗粒。这些囊泡包含一种生物相容性聚合物，通过用一个或多个磷脂单体涂覆全氟化合物颗粒并聚合这些单体来形成。
• EP0417104A4
  申请人：——

  公开号：EP0417104A4

  公开（公告）日：1991-10-30
• PERFLUOROCHEMICAL EMULSION WITH STABILIZED VESICLES
  申请人：ALPHA THERAPEUTIC CORPORATION

  公开号：EP0417104A1

  公开（公告）日：1991-03-20
• GAS-FILLED STABILIZED PARTICLES AND METHODS OF USE
  申请人：CHILDREN'S MEDICAL CENTER CORPORATION

  公开号：US20160030596A1

  公开（公告）日：2016-02-04

  Provided herein are various gas-filled particles having a stabilized membrane that encapsulates the gas. Pharmaceutical compositions, methods of use and treatment, and methods of preparation are also described.
• METHODS OF NANOSCALE DIRECTIONAL WETTING AND USES THEREOF
  申请人：Purdue Research Foundation

  公开号：US20200061667A1

  公开（公告）日：2020-02-27

  This invention discloses a method for controlling nanoscopic wetting near or at a molecular scale for synthetic material applications. In particular this invention relates to a method for preparing a monolayer or thin film with a patterned nanoscopic wetting surface using a ‘sitting’ phase of polymerizable amphiphile, wherein hydrophobic alkyl chains of the amphiphile extend along the supporting surface and the amphiphile molecules align side-to-side, effectively forming a repeating cross-section of bilayer with alternating hydrophilic and hydrophobic stripes of a ˜6 nm pitch tunable based on the chain length of the amphiphile. Products prepared according to the methods disclosed herein are within the scope of this invention. In some embodiments, monolayers or thin films so prepared are transferable.