Efficient NaOH-Catalyzed Reaction of Aromatic Aldehyde, Cyclic Ketones, and Malononitrile Under Solvent-Free Conditions Using a Grinding Method
作者:Liangce Rong、Hongxia Han、Hong Jiang、Shujiang Tu
DOI:10.1080/00397910802164724
日期:2008.9.29
Abstract An efficient and facilesynthesis of 2,6-dicyanoanilines via a one-pot reaction of aromatic aldehydes, malononitrile, and cyclic ketones in the presence of NaOH undersolvent-freeconditions using a grinding method has been developed. Compared with the classical reaction conditions, the new synthetic method has the advantages of excellent yields, shorter reaction times, and mild reaction conditions