1,3-Dimethyl-1,2,3,4-tetrahydro-β-carbolin | 6678-83-7

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 哈马拉生物碱
• 英文名称: 1,3-Dimethyl-1,2,3,4-tetrahydro-β-carbolin
• 英文别名: 1,3-dimethyl-2,3,4,9-tetrahydro-1H-β-carboline；1,3-Dimethyl-2,3,4,9-tetrahydro-1H-beta-carboline；1,3-dimethyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
• CAS: 6678-83-7
• 化学式: C₁₃H₁₆N₂
• mdl: MFCD00617631
• 分子量: 200.283
• InChiKey: WPILWEFRBGMVDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.384
• 拓扑面积：
  27.8
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• ß-CARBOLINE, DIHYDRO-ß-CARBOLINE AND TETRAHYDRO-ß-CARBOLINE ALKALOID DERIVATIVES AND PREPARATION METHODS SAME AND USE IN ASPECTS OF PREVENTING AND TREATING PLANT VIRUSES, FUNGICIDES AND INSECTICIDES
  申请人：NANKAI UNIVERSITY

  公开号：US20160326166A1

  公开（公告）日：2016-11-10

  The present invention relates to β-carboline, dihydro-β-carboline and tetrahydro-β-carboline alkaloid derivatives (I) and a method for preparing same and the use in the aspects of preventing and treating plant viruses, fungicides and insecticides. For the meaning of each group in formula (I) see the description. The β-carboline, dihydro-β-carboline and tetrahydro-β-carboline alkaloid derivatives of the present invention show a particularly ourstanding anti-plant virus activity, and also have fungicidal and insecticidal activities.

  本发明涉及β-咔啉、二氢β-咔啉和四氢β-咔啉生物碱衍生物(I)，以及其制备方法和在预防和治疗植物病毒、杀菌剂和杀虫剂方面的用途。本发明中的β-咔啉、二氢β-咔啉和四氢β-咔啉生物碱衍生物显示出特别出色的抗植物病毒活性，同时还具有杀菌和杀虫活性。
• HETEROARYL ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
  申请人：F. Hoffmann-La Roche AG

  公开号：EP3472162B1

  公开（公告）日：2021-11-17