3,7-Dibromophenothiazin-5-ium

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: 3,7-Dibromophenothiazin-5-ium
• 化学式: C12H6Br2NS+
• 分子量: 356.06
• InChiKey: CUWDHSMQTYKBGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.26
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  41.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Multifunctional Radical Quenchers For The Treatment Of Mitochondrial Dysfunction
  申请人：Hecht Sidney

  公开号：US20140038963A1

  公开（公告）日：2014-02-06

  The present disclosure provides methods for identifying therapeutic agents that are multifunctional radical quenchers. It also provides compounds of formula (I), (II), or (II-A): and pharmaceutically acceptable salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications, such as treatment or suppression of diseases associated with decreased mitochondrial function resulting in diminished ATP production and/or oxidative stress and/or lipid peroxidation.

  本公开提供了一种识别多功能自由基清除剂的治疗剂的方法。还提供了式(I)、(II)或(II-A)的化合物及其药学上可接受的盐、包含这些化合物的组合物和使用这些化合物的方法，例如用于治疗或抑制与线粒体功能下降导致ATP产生减少和/或氧化应激和/或脂质过氧化相关的疾病。
• PROCESSES FOR PREPARING NOVEL METHYLENE BLUE DERIVATIVE
  申请人：Vig Rakesh

  公开号：US20070129543A1

  公开（公告）日：2007-06-07

  Methods for the preparation of 7-(dipropylamino)pheno-thiazin-3-ylidene]-dipropylamine
• Antiviral Treatments
  申请人：Plattner Jacob

  公开号：US20110178071A1

  公开（公告）日：2011-07-21

  Compounds and methods for preventing and treating viral infections are provided. In some embodiments, novel compounds broad-spectrum antiviral activity are provided. In more specific embodiments, the compounds and methods are effective against viruses such as Venezuelan Equine Encephalitis, West Nile Virus, and Hepatitis C.
• US7176308B2
  申请人：——

  公开号：US7176308B2

  公开（公告）日：2007-02-13
• US8227459B2
  申请人：——

  公开号：US8227459B2

  公开（公告）日：2012-07-24