3-[3,4-dihydro-7-fluoro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione | 134553-67-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 3-[3,4-dihydro-7-fluoro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione
• 英文别名: 3-(7-fluoro-3-oxo-4-propargyl-2H-1,4-benzoxazin-6-yl)-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione；1-[7-fluoro-4-propargyl-2H-1,4-benzoxazin-3(4H)-on-6-yl]-4-trifluoromethyl-1,2,3,6-tetrahydropyrimidine-2,6-dione；3-(7-fluoro-3-oxo-4-prop-2-ynyl-1,4-benzoxazin-6-yl)-6-(trifluoromethyl)-1H-pyrimidine-2,4-dione
• CAS: 134553-67-6
• 化学式: C₁₆H₉F₄N₃O₄
• 分子量: 383.259
• InChiKey: IGIGTBWGKVOSMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  27
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  79
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  3-[3,4-dihydro-7-fluoro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione 、 硫酸二甲酯 以 N-甲基乙酰胺 、 正己烷 、 水 、 乙酸乙酯 为溶剂， 生成 3-(7-fluoro-3-oxo-4-propargyl-2H-1,4-benzoxazin-6-yl)-1-methyl-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione
  参考文献：
  名称：

  Uracil derivatives and herbicides containing the same as active

  摘要：

  本文公开了一种尿嘧啶衍生物，其在6位具有卤代烷基，在3位具有具有特定取代基的苯基，其由式（I）表示，具有渗透移行活性和非常高的除草活性，与传统的除草化合物相比，该尿嘧啶衍生物可用于土壤处理或叶面处理，从而在非常低的剂量下对包括多年生杂草在内的各种杂草产生快速和高效的除草效果，并具有适当时间的残留效果。

  公开号：

  US05084084A1
• 作为产物：
  描述：

  7-fluoro-6-methoxycarbonylamino-4-propargyl-2H-1,4-benzoxazin-3(4H)-one 、 乙基3-氨基-4,4,4-三氟-2-丁烯酸酯 以 N-甲基乙酰胺 为溶剂， 生成 3-[3,4-dihydro-7-fluoro-3-oxo-4-(2-propynyl)-2H-1,4-benzoxazin-6-yl]-6-trifluoromethyl-2,4(1H,3H)-pyrimidinedione
  参考文献：
  名称：

  N-aminouracil derivatives, and their production and use

  摘要：

  该化合物的化学式为：##STR1## 其中R.sup.1是三氟甲基基团或五氟乙基基团，R.sup.2是氢原子或甲基基团，R.sup.3是C.sub.1-C.sub.7烷基基团，C.sub.3-C.sub.7烯基基团，C.sub.3-C.sub.7炔基基团，卤(C.sub.1-C.sub.6)烷基团，卤(C.sub.3-C.sub.6)烯基团或C.sub.1-C.sub.4烷氧基(C.sub.1-C.sub.3)烷基团，X是氢原子或氟原子，可用作除草剂。

  公开号：

  US05314864A1

文献信息

• Heterocyclic substituted uracil derivatives
  申请人：Ciba-Geigy Corporation

  公开号：US05232898A1

  公开（公告）日：1993-08-03

  The invention is concerned with compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, n and X have the significances given in the description, as well as enol ethers and salts thereof and their manufacture. The compounds have herbicidal properties and are accordingly suitable as active ingredients of weed control compositions. The invention is also concerned with weed control compositions containing one or more of such substances as well as the use of the substances or compositions for the control of weeds. Certain starting materials, which also have herbicidal activity, and their production are also described.

  这项发明涉及以下结构的化合物##STR1##其中R.sup.1、R.sup.2、R.sup.3、R.sup.4、R.sup.5、R.sup.6、R.sup.7、n和X的含义如描述中所示，以及烯醚及其盐和制备方法。这些化合物具有除草特性，因此适用作为除草剂配方的活性成分。该发明还涉及含有一种或多种这类物质的除草剂配方，以及利用这些物质或配方控制杂草。还描述了具有除草活性的某些起始材料及其生产。
• Process for producing 3-phenyluracil compounds
  申请人：Sumitomo Chemical Company, Limited

  公开号：US06339155B1

  公开（公告）日：2002-01-15

  The uracil compounds represented by the formula [V]: wherein R1 represents C1-C5 perfluoroalkyl group and Q represents an aromatic group, can be produced by making the amide compounds represented by the formula [II]: wherein R1 and Q have the same meanings defined above, or its hydrate react with a cyanate salt in the presence of a protonic acid.

  由公式[V]表示的尿嘧啶化合物：其中R1代表C1-C5全氟烷基基团，Q代表芳香族基团，可以通过使由公式[II]表示的酰胺化合物：其中R1和Q具有上述定义的相同含义，或其水合物与氰酸盐在质子酸存在下反应而制得。
• Uracil derivatives and herbicides containing the same as active ingredient
  申请人：NISSAN CHEMICAL INDUSTRIES, LIMITED

  公开号：EP0408382A2

  公开（公告）日：1991-01-16

  Disclosed herein is uracil derivatives having a haloalkyl group at the 5-position and a phenyl group at the 2- position which has a specific substituent, which are represented by the formula (I) and showing penetrative translocation activity and a very high herbicidal activity, in which as compared with the conventional herbicidal compounds, the said uracil derivatives can be applied for either soil treatment or foliage treatment, thereby producing a quick and high herbicidal effect even at a very low dosage against a large variety of weeds including perennial weeds. and have the property to residual effect for an appropriate period of time.

  此处公开的脲嘧啶衍生物在 5-位上有一个卤代烷基，在 2-位上有一个具有特定取代基的苯基，它们由式（I）表示，具有穿透性转座活性和极高的除草活性，与传统的除草化合物相比，上述脲嘧啶衍生物既可用于土壤处理，也可用于叶面处理，因此即使用量极低，也能对包括多年生杂草在内的多种杂草产生快速、高效的除草效果。并且在适当的时间内具有残留效果。
• Uracil derivatives and their production and use
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0420194A2

  公开（公告）日：1991-04-03

  A compound of the formula: wherein R1 is a trifluoromethyl group or a pentafluoroethyl group, R2 is a methyl group or an amino group and Q is either one of the formulas: wherein R3 is a hydrogen atom or a methyl group, R4, R5 and R6 are each a C1-C7 alkyl group, a C3-C7 alkenyl group, a C3-C7 alkynyl group, a halo(C1-C6)alkyl group, a halo(C3-C6)alkenyl group or a C1-C4 alkoxy(C1-C3)-alkyl group, X is a hydrogen atom or a fluorine atom and Y is an oxygen atom or a sulfur atom, with the proviso that when Q is Q3, R2 represents a methyl group, which is useful as a herbicide.

  以下式子的化合物 其中 R1 为三氟甲基或五氟乙基，R2 为甲基或氨基，Q 为下列式子之一 其中 R3 是氢原子或甲基，R4、R5 和 R6 分别是 C1-C7 烷基、C3-C7 烯基、C3-C7 炔基、卤代（C1-C6）烷基、卤代（C3-C6）烯基或 C1-C4 烷氧基（C1-C3）-烷基，X 是氢原子或氟原子，Y 是氧原子或硫原子，但当 Q 为 Q3 时，R2 代表甲基，可用作除草剂。
• US5084084A
  申请人：——

  公开号：US5084084A

  公开（公告）日：1992-01-28