2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl methacrylate | 34649-63-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl methacrylate
• 英文别名: 2-(2-tetrahydropyranyloxy)ethyl methacrylate；2-(Oxan-2-yloxy)ethyl 2-methylprop-2-enoate
• CAS: 34649-63-3
• 化学式: C₁₁H₁₈O₄
• 分子量: 214.262
• InChiKey: ZVSJTZDSQBQYFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3,4-二氢-2H-吡喃 、 甲基丙烯酸羟乙酯 在 C₃₂H₁₂F₁₀O₂ 、 二苯二硫醚 作用下， 以 二氯甲烷 为溶剂， 反应 6.0h， 以66%的产率得到2-((tetrahydro-2H-pyran-2-yl)oxy)ethyl methacrylate
  参考文献：
  名称：

  BINOLs作为光酸催化剂在可见光照射下与醇缩醛化

  摘要：

  适当取代的 1,1'-bi-2-naphthols (BINOLs) 被证明是在可见光照射下促进烯醇醚与醇缩醛化的有效光酸催化剂。在温和、接近中性的条件下，反应可在多种底物上有效进行。

  DOI：

  10.1055/a-1799-7464

文献信息

• CARBOHYDRATE-BASED COMPOSITIONS AND METHODS FOR TARGETED DRUG DELIVERY
  申请人：Stayton Patrick

  公开号：US20140235790A1

  公开（公告）日：2014-08-21

  Provided herein are compositions and methods for intracellular delivery. The compositions are polymer compositions in which the polymer serves as a carrier for therapeutic and/or diagnostic agents. The polymer compositions are effective in targeted delivery of therapeutic and/or diagnostic agents to a cell. The polymer compositions include a targeting moiety that includes carbohydrate groups that effectively target specific cell surface receptors. The polymer compositions also include an agent binding moiety that effectively associates the therapeutic and/or diagnostic agent to be delivered to the cell.

  本文提供了一种用于细胞内递送的组合物和方法。这些组合物是聚合物组合物，其中聚合物作为治疗和/或诊断试剂的载体。这些聚合物组合物在将治疗和/或诊断试剂有针对性地递送至细胞方面非常有效。这些聚合物组合物包括一个包含碳水化合物基团的靶向部分，有效地靶向特定的细胞表面受体。这些聚合物组合物还包括一个结合部分，有效地将待递送至细胞的治疗和/或诊断试剂与之结合。
• Anionic living polymers, their derivatives and composition comprising them
  申请人：DAINIPPON INK AND CHEMICALS, INC.

  公开号：EP0465835A1

  公开（公告）日：1992-01-15

  The methacrylic ester polymers produced according to this invention are uniquely distinguished from the radically prepared polymers of similar composition by the fact that both polymers produced: by anionic living polymerization and by deactivating the active terminals of anionic living polymers; contain acetal and/or ketal groups as the blocked hydroxyl groups and have narrow molecular weight distribution. Hydroxyl group-containing methacrylic acid ester polymers are produced by hydrolysis of the above-mentioned polymers. The anionic living polymers are produced in high yields by anionically polymerizing methacrylic acid esters containing an acetal or ketal group in the presence of initiators such as alkaline metal alkoxides. The polymers of the present invention can be used in various fields of applications such as coatings and adhesives. The polymers of the present invention yield curable high solids compositions.

  根据本发明生产的甲基丙烯酸酯聚合物与类似成分的辐射制备聚合物的独特区别在于：这两种聚合物都是通过阴离子活聚合和使阴离子活聚合物的活性末端失活而生产的；含有作为封端羟基的缩醛和/或缩酮基团，并且分子量分布较窄。含羟基的甲基丙烯酸酯聚合物是通过水解上述聚合物制得的。阴离子活聚合物是在碱金属烷氧基等引发剂存在下，通过阴离子聚合含缩醛或缩酮基团的甲基丙烯酸酯，以高产率生产出来的。本发明的聚合物可用于涂料和粘合剂等多个应用领域。本发明的聚合物可产生可固化的高固体成分。
• Klaikherd, Akamol; Nagamani, Chikkannagari; Thayumanavan, S., Journal of the American Chemical Society, 2009, vol. 131, p. 4830 - 4838
  作者：Klaikherd, Akamol、Nagamani, Chikkannagari、Thayumanavan, S.

  DOI：——

  日期：——
• Cleavable Block Copolymers, Functionalized Nanoporous Thin Films and Related Methods of Preparation
  申请人：Thayumanavan Sankaran

  公开号：US20090105427A1

  公开（公告）日：2009-04-23

  Cleavable, disulfide-coupled block copolymers as can be used in the preparation of nanoporous thin films, micellar configurations and related structures.
• Cleavable block copolymers, functionalized nanoporous thin films and related methods of preparation
  申请人：Thayumanavan Sankaran

  公开号：US20120245244A1

  公开（公告）日：2012-09-27

  Cleavable, disulfide-coupled block copolymers as can be used in the preparation of nanoporous thin films, micellar configurations and related structures.