7-(二甲氨基)吩恶嗪-3-酮 | 41830-79-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 中文名称: 7-(二甲氨基)吩恶嗪-3-酮
• 英文名称: 7-dimethylamino-phenoxazin-3-one
• 英文别名: 7-Dimethylamino-phenoxazin-3-on；7-(Dimethylamino)phenoxazin-3-one
• CAS: 41830-79-9
• 化学式: C₁₄H₁₂N₂O₂
• 分子量: 240.261
• InChiKey: BGEGWGMYXJBZTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 硫酸 、 亚硝酸异戊酯 作用下， 生成 7-(二甲氨基)吩恶嗪-3-酮
  参考文献：
  名称：

  Moehlau, Chemische Berichte, 1892, vol. 25, p. 1065

  摘要：

  DOI：

文献信息

• Azetidine-Containing Heterospirocycles Enhance the Performance of Fluorophores
  作者：Junliang Zhou、Xianfeng Lin、Xin Ji、Shuang Xu、Chang Liu、Xiaochun Dong、Weili Zhao

  DOI：10.1021/acs.orglett.0c01414

  日期：2020.6.5

  utilized in various fluorescence imaging techniques. However, many existing modification strategies could not balance the performance (such as brightness, photostability, water solubility, and permeability) of fluorophores. Herein we report a general strategy to enhance the performance of donor–acceptor-type fluorophores by introducing azetidine-containing heterospirocycles to the commonly used fluorophore

  荧光染料广泛用于各种荧光成像技术中。但是，许多现有的修饰策略无法平衡荧光团的性能（例如亮度，光稳定性，水溶性和渗透性）。本文中，我们报告了通过将含氮杂环丁烷的杂螺环引入常用的荧光支架中来增强供体-受体型荧光团性能的一般策略。事实证明，这种策略是开发高质量荧光团的一般方法。
• Method for detecting target substance, and tag, DNA, vector, probe and detection kit for use therewith
  申请人：Tamamura Hirokazu

  公开号：US20100075434A1

  公开（公告）日：2010-03-25

  Provide is a method for detecting a target substance, which method can visualize the expression of the target substance at any time point while reducing influences on the functions of the target substance, can use fluorescent dyes having various excitation/emission wavelengths, and can achieve easy staining process. Also provided are a tag, a DNA, a vector, a probe and a detection kit suitable for use in the above-described detection method. Specifically, the method for detecting a target substance, comprises the steps of bringing into contact with each other (a) a tag comprising a polypeptide forming an α-helix structure, the tag bound to the target substance, and (b) a probe comprising a compound bound to a fluorescent dye; and measuring the fluorescence emitted by the fluorescent dye. The binding of the tag α-helix structure to the probe compound induces a spectral change in the fluorescence emitted by the fluorescent dye.
• US8445291B2
  申请人：——

  公开号：US8445291B2

  公开（公告）日：2013-05-21