N,N-Diallyl-isopropyl-amin | 10542-47-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-Diallyl-isopropyl-amin
• 英文别名: N-(1-methylethyl)-N-2-propenyl-2-propen-1-amine；2-Propen-1-amine, N-(1-methylethyl)-N-2-propenyl-；N,N-bis(prop-2-enyl)propan-2-amine
• CAS: 10542-47-9
• 化学式: C₉H₁₇N
• 分子量: 139.241
• InChiKey: DFSQFCRJLMWKBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N,N-Diallyl-isopropyl-amin 在 氢氧化钾 、 二甲基亚砜 作用下， 反应 6.0h， 生成 1-乙基-3-甲基环己烷 、 isopropyl-dipropenyl-amine
  参考文献：
  名称：

  Unexpected Transformations of Alkyldiallylamines in the KOH-DMSO System

  摘要：

  Triallylamine in the KOH-DMSO system readily isomerizes into tri(1-propenyl)amine. Alkyldiallylamines in the same system give 1-ethyl-3-methylcyclohexane along with alkyldi(1-propenyl)amine. The effect of quantity of base and reaction temperature on product ratio was studied. A route of 1-ethyl-3-methyl-cyclohexane formation was proposed.

  DOI：

  10.1023/b:rugc.0000016025.63629.20
• 作为产物：
  描述：

  异丙胺 、 3-溴丙烯 在 potassium carbonate 作用下， 以 乙醚 为溶剂， 生成 N,N-Diallyl-isopropyl-amin
  参考文献：
  名称：

  The Sodium—Ammonia Reduction of Bispropargyl- and Propargylallylamines. Steric and Conformational Effects¹

  摘要：

  DOI：

  10.1021/jo01344a510

文献信息

• Bisphosphonates as inhibitors of acid sphingomyelinase
  申请人：Humboldt Universität zu Berlin

  公开号：EP2289900A1

  公开（公告）日：2011-03-02

  The present invention refers to bisphosphonate and phosphonate/phosphate compounds of Formulae I and II and its use as inhibitors of aSMase enzyme activity.

  本发明涉及Formulae I和II的双膦酸盐和膦酸盐/磷酸盐化合物，以及其作为aSMase酶活性抑制剂的用途。
• TRIPEPTIDE COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF
  申请人：NORTHWEST UNIVERSITY

  公开号：US20170267718A1

  公开（公告）日：2017-09-21

  Provided are a tripeptide compound, a preparation method therefor, and an application thereof. The structure of the related compound is represented by formula (I). The provided compound has angiotensin converting enzyme inhibiting bioactivity, and the compound and a pharmaceutical composition thereof play a role in preventing and treating hypertension and other cardiocerebral vascular system diseases.

  提供了一种三肽化合物，其制备方法和应用。相关化合物的结构由式（I）表示。提供的化合物具有抑制血管紧张素转换酶的生物活性，该化合物及其药物组成对预防和治疗高血压和其他心脑血管系统疾病起着作用。
• PARAMYXOVIRUS FAMILY INHIBITORS AND METHODS OF USE THEREOF
  申请人：Plemper Richard K.

  公开号：US20110160188A1

  公开（公告）日：2011-06-30

  Embodiments of the present disclosure include methods for identifying a compound or compounds useful as therapeutic agents in the treatment of paramyxovirus infections, compounds for the treatment of measles, and high throughput screening methods for identifying compounds capable of inhibiting the proliferation of a paramyxovirus.

  本公开的实施例包括用于识别化合物或化合物的方法，这些化合物在治疗副黏病毒感染方面作为治疗剂有用，用于麻疹治疗的化合物，以及用于识别能够抑制副黏病毒增殖的化合物的高通量筛选方法。
• [EN] REACTIVE TYPE PHOSPHATE AND PREPARATION PROCESS<br/>[FR] PHOSPHATE DE TYPE RÉACTIF ET PROCÉDÉ DE PRÉPARATION
  申请人：BLUE CUBE IP LLC

  公开号：WO2021237695A1

  公开（公告）日：2021-12-02

  Provided herein are phosphorus-based flame retardant compounds that provide both good electrical characteristics and good heat resistance characteristics when incorporated into PCB compositions. In particular, provided herein are new organophosphorus-based polymers that contain C=C double bonds, which allows them react with other components (for example, C=C bond capped polyphenyl ether, unsaturated hydrocarbon resin, bismaleic imide, etc. ) to form a crosslinked network.

  本文提供了一些基于磷的阻燃化合物，当它们被加入到PCB组成中时，可以同时提供良好的电特性和热阻特性。特别地，本文提供了一些含有C=C双键的新型有机磷聚合物，这使它们能够与其他组分（例如，C=C键封端的聚苯醚、不饱和烃树脂、双马来酰亚胺等）反应，形成交联网络。
• Aminoquinoline Derived Heat Shock Protein 90 Inhibitors, Methods Of Preparing Same, And Methods For Their Use
  申请人：Sun Aiming

  公开号：US20110281908A1

  公开（公告）日：2011-11-17

  Novel classes of molecular chaperone Heat shock protein 90 (Hsp90) inhibitors and methods for making these classes are provided herein. These compounds are useful in treating and preventing cancer and other Hsp90-related diseases, such as inflammation and neurodegenerative disorders. Also provided herein are methods of treating and preventing cancer and other Hsp90 related disease. The methods include administering to a subject a therapeutically effective amount of an Hsp90 inhibitor.

  本文提供了新型分子伴侣热休克蛋白90（Hsp90）抑制剂的类别和制备方法。这些化合物可用于治疗和预防癌症和其他与Hsp90相关的疾病，如炎症和神经退行性疾病。本文还提供了治疗和预防癌症和其他Hsp90相关疾病的方法。该方法包括向患者施用治疗有效量的Hsp90抑制剂。

表征谱图