H-Thr-Ser-Leu-Asp-Ala-Ser-Ile-Ile-Trp-Ala-Met-Met-Gln-DL-Asn-OH

• 分子结构分类: 有机化合物 - 有机聚合物 - 多肽
• 英文名称: H-Thr-Ser-Leu-Asp-Ala-Ser-Ile-Ile-Trp-Ala-Met-Met-Gln-DL-Asn-OH
• 英文别名: 4-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-carboxypropanoyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-oxopentanoyl]amino]-4-oxobutanoic acid
• 化学式: C₆₈H₁₀₉N₁₇O₂₂S₂
• 分子量: 1580.8
• InChiKey: IUYPEUHIWDMJLM-CSRSNMFNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.6
• 重原子数：
  109
• 可旋转键数：
  51
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  692
• 氢给体数：
  22
• 氢受体数：
  25

文献信息

• Methods, compositions, and kits for producing beige adipocytes and treating metabolic disorders
  申请人：Maine Medical Center Research Institute

  公开号：US11279915B2

  公开（公告）日：2022-03-22

  Provided herein are, inter alia, methods, compositions, and kits for producing adipocyte populations such as beige adipocyte populations. Also included are methods and compositions for increasing the level of adipocyte populations (e.g., beige adipocyte populations) in a subject, as well as methods and compositions for treating subjects who are overweight, obese, or who have diabetes.

  本文特别提供了生产脂肪细胞群（如米色脂肪细胞群）的方法、组合物和试剂盒。还包括用于提高受试者体内脂肪细胞群（如米色脂肪细胞群）水平的方法和组合物，以及用于治疗超重、肥胖或糖尿病受试者的方法和组合物。
• METHODS, COMPOSITIONS, AND KITS FOR PRODUCING BEIGE ADIPOCYTES AND TREATING METABOLIC DISORDERS
  申请人：Maine Medical Center Research Institute

  公开号：US20190264178A1

  公开（公告）日：2019-08-29

  Provided herein are, inter alia, methods, compositions, and kits for producing adipocyte populations such as beige adipocyte populations. Also included are methods and compositions for increasing the level of adipocyte populations (e.g., beige adipocyte populations) in a subject, as well as methods and compositions for treating subjects who are overweight, obese, or who have diabetes.