hydron;1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indol-7-one;chloride

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 哈马拉生物碱
• 英文名称: hydron;1-methyl-2,3,4,9-tetrahydropyrido[3,4-b]indol-7-one;chloride
• 化学式: C12H13ClN2O
• 分子量: 236.7
• InChiKey: LRNHCUPADIPJOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.22
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  41.1
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• COMBINATION PRODUCT FOR THE TREATMENT OF NEUROLOGICAL AND/OR PSYCHIATRIC DISORDERS
  申请人：Consejo Superior de Investigaciones Científicas (CSIC)

  公开号：EP3713568A1

  公开（公告）日：2020-09-30
• REGULATION OF GENE EXPRESSION BY MODULATING PRIMARY CILIA LENGTH
  申请人：THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

  公开号：US20190015423A1

  公开（公告）日：2019-01-17

  The presently disclosed subject matter relates to methods of regulating gene expression in a cell by modulating the length of primary cilia of a cell, wherein such modulation can modulate the mechanosensitivity of the cell. The presently disclosed subject matter also provides for methods of treating ciliopathies and osteoporosis in a subject by increasing the length of primary cilia of a cell in a subject.
• COMPOSITION FOR TREATING BURN WOUNDS
  申请人：XIE Yan

  公开号：US20210401786A1

  公开（公告）日：2021-12-30

  The invention provides a composition for treating a burn wound, comprising a variety of ingredients, including a fatty acid 261-639 mg, an organic substance 3.5-350 mg, a carbohydrate 0.02-60 mg, a vitamin 9-13 μg, a microelement 3.04-5.5 mg, an antibiotic 0.6-70 mg, and an amino acid 105-335 mg. The significant therapeutic effects of the invention include effectively promoting repair of a burn wound, anti-infection, inhibiting scar hyperplasia, no toxic side effect, convenient use, fast absorption, economical efficiency, etc. The invention provides patients with an efficient, economical, convenient and practical treatment for burn wounds, which greatly reduces the burden on patients, and effectively compensates for the various deficiencies of the current treatments for the non-healing burn wounds.