S-(1,3-benzothiazol-2-yl) 4-methylbenzenecarbothioate | 353258-60-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: S-(1,3-benzothiazol-2-yl) 4-methylbenzenecarbothioate
• CAS: 353258-60-3
• 化学式: C₁₅H₁₁NOS₂
• 分子量: 285.39
• InChiKey: JTOOFWWLGBHMQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  83.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  对甲基苯甲酰氯 、 2-巯基苯并噻唑 在 吡啶 作用下， 以 四氢呋喃 为溶剂， 反应 0.08h， 生成 S-(1,3-benzothiazol-2-yl) 4-methylbenzenecarbothioate
  参考文献：
  名称：

  Ultrasound promoted synthesis of thioesters from 2-mercaptobenzoxa(thia)zoles

  摘要：

  An ultrasound-enhanced method has been developed for the synthesis of a variety of thioesters from benzoyl chlorides and 2-mercaptobenzoxa(thia)zoles. Applying this methodology, 14 compounds were synthesized in excellent yields. (C) 2009 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ultsonch.2009.08.004

文献信息

• Ultrasound promoted synthesis of thioesters from 2-mercaptobenzoxa(thia)zoles
  作者：Anaí Duarte、Wilson Cunico、Claudio M.P. Pereira、Alex F.C. Flores、Rogério A. Freitag、Geonir M. Siqueira

  DOI：10.1016/j.ultsonch.2009.08.004

  日期：2010.2

  An ultrasound-enhanced method has been developed for the synthesis of a variety of thioesters from benzoyl chlorides and 2-mercaptobenzoxa(thia)zoles. Applying this methodology, 14 compounds were synthesized in excellent yields. (C) 2009 Elsevier B.V. All rights reserved.