methyl-n-octyldiallylammonium bromide | 69419-86-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: methyl-n-octyldiallylammonium bromide
• 英文别名: n-Octylmethyldiallylammonium bromide；methyl octyl diallyl ammonium bromide；Methyl-octyl-bis(prop-2-enyl)azanium;bromide
• CAS: 69419-86-9
• 化学式: Br*C₁₅H₃₀N
• 分子量: 304.314
• InChiKey: ZIABPLKWMIVKSA-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.17
• 重原子数：
  17
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-甲基二烯丙基胺 、 1-溴辛烷 以 丙酮 为溶剂， 反应 480.0h， 以51%的产率得到methyl-n-octyldiallylammonium bromide
  参考文献：
  名称：

  Synthesis and catalytic properties of hydrophobically modified poly(alkylmethyldiallylammonium bromides)

  摘要：

  A series of hydrophobically modified homo- and copolymers of the poly(alkylmethyldiallylammonium bromide) type has been prepared by free-radical cyclo(co)polymerization of alkylmethyldiallylammonium bromide monomers in aqueous solution. Depending on the length of the alkyl side chain (varied between C1 and C-12) and the conformational freedom of the polymeric main chain, polysoap behavior was found as indicated by the hypsochromic shift of the long-wavelength absorption band of Methyl Orange, noncovalently bound to the macromolecule. The formation of a compact coil results in the presence of hydrophobic microdomains. Polysoap formation, akin to intramolecular micellization, is also revealed by appreciable catalytic effects on the unimolecular decarboxylation of 6-nitrobenzisoxazole-3-carboxylate at pH 11.3 and 30-degrees-C.

  DOI：

  10.1021/jo00013a043

文献信息

• POLYSACCHARIDE-BASED GRAFT COPOLYMER AND COMPOSITION COMPRISING SAME FOR PERSONAL CARE
  申请人：Kci Limited

  公开号：EP2660252A2

  公开（公告）日：2013-11-06

  The present invention relates to a graft copolymer including a polysaccharide as a main chain and a phosphorylcholine analogous group-containing monomer as a side chain, and a composition for skin and hair care including the copolymer as an active ingredient. The graft copolymer according to the present invention exhibits more improved moisturizing capacity and better biocompatibility than the existing polysaccharide-based graft copolymer by introducing a phosphorylcholine analogous group-containing compound, and accordingly, the composition for hair and skin care including the same also has improved moisturizing capacity, protection capacity of damaged hair, skin affinity, a skin barrier function, and the like.

  本发明涉及一种包括作为主链的多糖和作为侧链的含磷酸胆碱类似基团单体的接枝共聚物，以及一种包括该共聚物作为活性成分的护肤和护发组合物。根据本发明的接枝共聚物通过引入含磷酸胆碱类似基团的化合物，比现有的多糖基接枝共聚物具有更高的保湿能力和更好的生物相容性，相应地，包括本发明的接枝共聚物的护发护肤组合物也具有更高的保湿能力、对受损头发的保护能力、皮肤亲和性、皮肤屏障功能等。
• Synthesis and Catalytic Properties of Non-Cross-Linked and Cross-Linked Poly(alkylmethyldiallylammonium bromides) Having Decyl, Octyl, and Hexyl Side Chains
  作者：Guang-Jia Wang、Jan B. F. N. Engberts

  DOI：10.1021/jo00118a020

  日期：1995.6

  A family of non-cross-linked and cross-linked copolymers containing decyl, octyl, and hexyl groups as side chains ((CL)-CopolC1-10, (CL)-CopolC1-8, and (CL)-CopolC1-6, respectively) were synthesized by radical-initiated cyclocopolymerization of alkylmethyldiallylammonium bromide monomers without and with a small amount of N,N'-methylenebisacrylamide as a cross-linking agent in aqueous solution. Their H-1 NMR and IR spectra indicated the presence of five-membered rings cross-linked without and with N,N'-methylenebisacrylamide in the macromolecules. Viscosity measurements showed that the cross-linked copolymers exhibit a larger reduced viscosity in aqueous solution with increasing cross-linking agent content in the copolymers. For(CL)-CopolC1-10, the conformational transition to compact coils was indicated by changes of the reduced viscosity in dilute aqueous solutions. At higher concentrations, intermolecular aggregation was also revealed and increased with increasing the percentage of cross-linking for CL-CopolC1-10. (CL)-CopolC1-8 and (CL)-CopolC1-6 showed extented molecular dimensions in aqueous solution. The hydrophobic microdomains of the non-cross-linked and cross-linked copolymers were probed by hypsochromic shifts of the long-wavelength absorption band of Methyl Orange as a solvatochromic agent, noncovalently bound to the macromolecule. The unimolecular decarboxylation of 6-nitrobenzisox-azole-3-carboxylate (6-NBIC), catalyzed by these copolymers in aqueous solution, was used as a model reaction to study the influence of polysoap microenviroment on reactivity. Depending on the hydrophobic group content, (CL)-CopolC1-10 led to a remarkably large rate enhancement, whereas (CL)-CopolC1-8 induced only modest rate acceleration for the decarboxylation of 6-NBIC. A small rate enhancement was observed in the presence of(CL)-CopolC1-6. The decarboxylation rate is also sensitive to changes of the percentage of cross-linking in the macromolecules. A maximum in rate constant was found at about 0.2% (w/w) cross-linking agent for CL-CopolC1-10 and at about 0.4% (w/w) for CL-CopolC1-8 in plots of the rate constant vs cross-linking agent content.
• YANG, YA JIANG;ENGBERTS, JAN B. F. N., J. ORG. CHEM., 56,(1991) N3, C. 4300-4304
  作者：YANG, YA JIANG、ENGBERTS, JAN B. F. N.

  DOI：——

  日期：——
• US4348380A
  申请人：——

  公开号：US4348380A

  公开（公告）日：1982-09-07
• US4410709A
  申请人：——

  公开号：US4410709A

  公开（公告）日：1983-10-18