N-pentylnonan-1-amine | 70655-47-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-pentylnonan-1-amine
• 英文别名: n-Amylnonylamine
• CAS: 70655-47-9
• 化学式: C₁₄H₃₁N
• mdl: MFCD03551904
• 分子量: 213.407
• InChiKey: YUIYZUGZYBDVIL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  15
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-nonyl-valeric acid amide 、 氢化铝锂 生成 N-pentylnonan-1-amine
  参考文献：
  名称：

  GALL, RUDI;BOSIES, ELMAR

  摘要：

  DOI：

文献信息

• Phosphine‐ and Hydrogen‐Free: Highly Regioselective Ruthenium‐Catalyzed Hydroaminomethylation of Olefins
  作者：Samet Gülak、Lipeng Wu、Qiang Liu、Robert Franke、Ralf Jackstell、Matthias Beller

  DOI：10.1002/anie.201402368

  日期：2014.7.7

  A highly regioselective ruthenium‐catalyzed hydroaminomethylation of olefins is reported. Using easily available trirutheniumdodecacarbonyl an efficient sequence consisting of a water‐gas shift reaction, hydroformylation of olefins, with subsequent imine or enamine formation and final reduction is realized. This novel procedure is highly practical (ligand‐free, one pot) and economic (low catalyst loading

  据报道，烯烃具有高度区域选择性的钌催化的氢氨基甲基化作用。使用容易获得的十二烷基三羰基羰基化合物，可以实现由水煤气变换反应，烯烃的加氢甲酰化，随后的亚胺或烯胺形成以及最终的还原反应组成的有效序列。这种新颖的方法非常实用（无配体，一锅），经济（催化剂用量低，金属价格便宜）。本体工业的以及官能化的烯烃与各种胺反应，通常以高收率（高达92％），优异的区域选择性（n / iso > 99：1）和对终端烯烃有利的全化学选择性，得到相应的叔胺。
• NOVEL CALCIUM CHANNEL DRUGS AND USES
  申请人：——

  公开号：US20030073127A1

  公开（公告）日：2003-04-17

  Novel multibinding compounds are disclosed. The compounds of this invention comprise 2-10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Ca ++ channel , thereby modulating the biological activities thereof.

  本发明揭示了新型多结合化合物。该发明的化合物包括2-10个共价连接的配体，每个配体能够结合到Ca++通道中的一个配体结合位点，从而调节其生物活性。
• Novel therapeutic agents for membrane transporters
  申请人：——

  公开号：US20030044845A1

  公开（公告）日：2003-03-06

  Novel multi-binding compounds (agents) are disclosed which bind cell membrane transporters including ion channels, molecular transporters and ion pumps. The compounds of this invention comprise from 2 to 10 ligands each of which can bind to such cellular transporters to modulate the biological processes/functions thereof. Each of the ligands is covalently attached to a linker (framework) to provide for a multi-binding compound. The linker is selected such that the multi-binding compound exhibits increased modulation of the biological processes/functions of the transporter as compared to the aggregate of the individual ligand units made available for binding to the transporter.

  本发明揭示了一种新型多重结合化合物（试剂），其结合细胞膜转运体，包括离子通道、分子转运体和离子泵。本发明的化合物包括2到10个配体，每个配体都可以结合到这些细胞转运体上，以调节其生物过程/功能。每个配体都共价地连接到一个连接器（框架）上，以提供多重结合化合物。所选择的连接器是为了使多重结合化合物相比可用于结合转运体的单个配体单元的聚合体表现出增强的调节转运体的生物过程/功能的特性。
• Novel calcium channel drugs and uses
  申请人：——

  公开号：US20040242561A1

  公开（公告）日：2004-12-02

  Novel multibinding compounds are disclosed. The compounds of this invention comprise 2-10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Ca ++ channel, thereby modulating the biological activities thereof.

  本发明揭示了一种新型多结合化合物。该化合物包括2-10个共价连接的配体，每个配体都能够结合到钙离子通道的配体结合位点上，从而调节其生物活性。
• NOVEL ANTIBACTERIAL AGENTS
  申请人：Chen Qi-Qi

  公开号：US20050171010A1

  公开（公告）日：2005-08-04

  Novel antibacterial agents that act as multibinding agents are disclosed. The compounds of the invention comprise from 2-10 ligands covalently connected, each of said ligands being capable of binding to a transglycosylase enzyme substrate thereby modulating the biological processes/functions thereof.

  本发明揭示了一种作为多重结合剂的新型抗菌剂。该发明的化合物包括2-10个共价连接的配体，每个配体都能够结合到转醣基酶（transglycosylase）酶底物上，从而调节其生物过程/功能。