10-n-Propyl-1,3-dichloro-7-amino-phenothiazine-5,5-dioxide | 35076-85-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: 10-n-Propyl-1,3-dichloro-7-amino-phenothiazine-5,5-dioxide
• 英文别名: 7,9-dichloro-5,5-dioxo-10-propylphenothiazin-3-amine
• CAS: 35076-85-8
• 化学式: C₁₅H₁₄Cl₂N₂O₂S
• 分子量: 357.3
• InChiKey: YXQLOAPVCIQVBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 海关编码：
  2934300000

文献信息

• EGR1 TARGETING MOLECULES FOR THE TREATMENT OF INFLAMMATORY AND HYPERPROLIFERATIVE CONDITIONS
  申请人：The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center

  公开号：EP3288547A1

  公开（公告）日：2018-03-07
• [EN] EGR1 TARGETING MOLECULES FOR THE TREATMENT OF INFLAMMATORY AND HYPERPROLIFERATIVE CONDITIONS<br/>[FR] MOLÉCULES DE CIBLAGE EGR1 DANS LE TRAITEMENT DE MALADIES INFLAMMATOIRES ET HYPERPROLIFÉRATIVES
  申请人：MEDICAL RES INFRASTRUCTURE & HEALTH SERVICES FUND TEL AVIV MEDICAL CT

  公开号：WO2016174674A1

  公开（公告）日：2016-11-03

  A method of treating an inflammation or a hyperproliferative disease in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of a compound selected from the group consisting of: a compound represented by Formula (I): or a pharmaceutically acceptable salt thereof, a compound represented by Formula (II): and a compound represented by Formula (III): wherein the variables in Formulae (I), (II) and (III) are as defined in the specification.