4-Dodecyloxycarbonyl-phthalimid | 33975-36-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 4-Dodecyloxycarbonyl-phthalimid
• 英文别名: 1,3-dioxo-1,3-dihydro-isoindole-5-carboxylic acid dodecyl ester；1H-Isoindole-5-carboxylic acid, 2,3-dihydro-1,3-dioxo-, dodecyl ester；dodecyl 1,3-dioxoisoindole-5-carboxylate
• CAS: 33975-36-9
• 化学式: C₂₁H₂₉NO₄
• 分子量: 359.466
• InChiKey: AYCPVHUVOLALSQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  26
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  72.5
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 4-Dodecyloxycarbonyl-phthalimid 以 甲醇 、 乙醚 为溶剂， 生成 Trimellithsaeure-1,2-dimethyl-4-n-dodecylester
  参考文献：
  名称：

  Mass spectrometry in structural and stereochemical problems. CCIII. Course of a triple hydrogen migration in esters of trimellitic anhydride

  摘要：

  DOI：

  10.1021/ja00745a014

文献信息

• METHOD FOR PRODUCING ORGANIC COMPOUND AND METHOD FOR DECOMPOSING COMPOUND HAVING DICARBOXYIMIDE SKELETON
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP1870394A1

  公开（公告）日：2007-12-26

  It is desirable to provide a method for easily removing catalyst-derived impurities from a product of a reaction by the catalysis of a compound having a dicarboximide skeleton and thereby efficiently yielding a target compound with high purity. Disclosed is a method for producing an organic compound through a reaction of a substrate in the presence of a catalyst, the catalyst including a compound having a dicarboximide skeleton represented by following Formula (i): wherein R represents hydrogen atom or a hydroxyl-protecting group. The method includes the step of treating a reaction product with hot water so as to decompose and remove an impurity derived from the catalyst. The temperature of the hot water is preferably 100°C or higher.

  希望提供一种方法，通过具有二甲酰亚胺骨架的化合物的催化作用，轻松去除反应产物中的催化剂衍生杂质，从而高效地获得高纯度的目标化合物。 本发明公开了一种在催化剂存在下通过底物反应生产有机化合物的方法，催化剂包括具有二甲酰亚胺骨架的化合物，其代表式如下式(i)： 其中 R 代表氢原子或羟基保护基团。该方法包括用热水处理反应产物的步骤，以便分解和除去来自催化剂的杂质。热水的温度最好为 100℃或更高。
• Method for Producing Organic Compound and Method for Decomposing Compound Having Dicarboximide Skeleton
  申请人：Hirai Naruhisa

  公开号：US20080171881A1

  公开（公告）日：2008-07-17

  It is desirable to provide a method for easily removing catalyst-derived impurities from a product of a reaction by the catalysis of a compound having a dicarboximide skeleton and thereby efficiently yielding a target compound with high purity. Disclosed is a method for producing an organic compound through a reaction of a substrate in the presence of a catalyst, the catalyst including a compound having a dicarboximide skeleton represented by following Formula (i): wherein R represents hydrogen atom or a hydroxyl-protecting group. The method includes the step of treating a reaction product with hot water so as to decompose and remove an impurity derived from the catalyst. The temperature of the hot water is preferably 100° C. or higher.
• US7994330B2
  申请人：——

  公开号：US7994330B2

  公开（公告）日：2011-08-09
• Mass spectrometry in structural and stereochemical problems. CCIII. Course of a triple hydrogen migration in esters of trimellitic anhydride
  作者：Carl Djerassi、John Cable

  DOI：10.1021/ja00745a014

  日期：1971.8