ethyl trimethylsilyl (3-bromopropyl)phosphonate | 918632-28-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: ethyl trimethylsilyl (3-bromopropyl)phosphonate
• 英文别名: Ethyl trimethylsilyl (3-bromopropyl)phosphonate；[3-bromopropyl(ethoxy)phosphoryl]oxy-trimethylsilane
• CAS: 918632-28-7
• 化学式: C₈H₂₀BrO₃PSi
• 分子量: 303.208
• InChiKey: NKQIJZKFAMGPPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.85
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  N,O-双三甲硅基乙酰胺 、 ethyl (3-bromopropyl)phosphonochloridate 以 乙醚 为溶剂， 反应 48.0h， 以57%的产率得到ethyl trimethylsilyl (3-bromopropyl)phosphonate
  参考文献：
  名称：

  Experimental and theoretical investigation of intramolecular transformations of silicon-containing (haloalkyl)phosphorylated ureas and acylamides

  摘要：

  Silicon-containing chloromethylphosphorylated ureas undergo transformation involving evolution of chlorotrimethylsilane and formation of 1,3,4-oxazaphospholes. Their analogs, silicon-containing phosphorylated acylamides, transform in another way, viz. by beta-cleavage to form the corresponding siloxyphosphonates. Quantum-chemical investigation of thermodynamic characteristics of these processes was carried out.

  DOI：

  10.1134/s1070363206030078

文献信息

• Reaction of dibromoalkanes with silyl phosphites. Synthesis and properties of mono-and diphosphonoalkanes
  作者：M. A. Pudovik、S. A. Terent’eva、L. K. Kibardina、A. N. Pudovik

  DOI：10.1134/s1070363206050094

  日期：2006.5

  Reactions of dibromoethane and dibromopropane with silyl phosphites are studied. Mono- and diphosphonoalkanes of various structures were prepared, and their chemical properties were studied.