2H-pyran, tetrahydro-2,5-dimethyl-, (2S,5R)-

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2H-pyran, tetrahydro-2,5-dimethyl-, (2S,5R)-
• 英文别名: (2S,5R)-2,5-dimethyloxane
• 化学式: C₇H₁₄O
• 分子量: 114.19
• InChiKey: YEJCHVFCLNKZPU-RQJHMYQMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AS AGGRECANASE INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS
  申请人：MERCK PATENT GMBH

  公开号：US20150368188A1

  公开（公告）日：2015-12-24

  The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which ADAMTS5 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.

  本发明涉及公式I的化合物，特别是包括至少一种公式I的化合物的药物，用于治疗和/或预防生理和/或病理状态，在其中ADAMTS5参与诱发，特别是用于治疗和/或预防骨关节炎、肝硬化、创伤性软骨损伤、疼痛、触发性痛或过敏性痛。
• LIQUID-CRYSTAL MEDIA AND LIGHT MODULATION ELEMENT
  申请人：Merck Patent GmbH

  公开号：EP3214154A1

  公开（公告）日：2017-09-06

  The present invention relates to liquid crystalline (LC) medium, to a method of its production and to the use of such LC media in polymer network liquid crystalline (PNLC) light modulation elements operated in the reverse mode. Furthermore, the present invention relates to such light modulation elements, as such, to the use of such light modulation elements as light shutters for transparent OLED displays, and to a method of production of such light modulation elements according to the present invention.

  本发明涉及液晶（LC）介质、其生产方法以及在以反向模式运行的聚合物网络液晶（PNLC）光调制元件中使用这种液晶介质。此外，本发明还涉及此类光调制元件、将此类光调制元件用作透明有机发光二极管显示器的光快门，以及根据本发明生产此类光调制元件的方法。
• Liquid crystal composition and liquid crystal display device
  申请人：JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD.

  公开号：US11359140B2

  公开（公告）日：2022-06-14

  Disclosed are a liquid crystal composition and a liquid crystal display device. The liquid crystal composition comprises at least one compound of general formula I, at least one compound of general formula II, at least one compound of general formula III, and at least one compound of general formula IV. By compounding the four compounds, the composition can have advantages of a wide temperature range of nematic phase, a low viscosity and a low threshold voltage, and the liquid crystal display element can have a short response time and great power saving performance.

  本发明公开了一种液晶组合物和一种液晶显示装置。液晶组合物包括至少一种通式 I 的化合物、至少一种通式 II 的化合物、至少一种通式 III 的化合物和至少一种通式 IV 的化合物。通过这四种化合物的复配，该组合物可以具有向列相温度范围宽、粘度低和阈值电压低的优点，液晶显示元件可以具有响应时间短和省电的性能。
• LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE
  申请人：JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD.

  公开号：US20200385635A1

  公开（公告）日：2020-12-10

  Disclosed are a liquid crystal composition and a liquid crystal display device. The liquid crystal composition comprises at least one compound of general formula I, at least one compound of general formula II, at least one compound of general formula III, and at least one compound of general formula IV. By compounding the four compounds, the composition can have advantages of a wide temperature range of nematic phase, a low viscosity and a low threshold voltage, and the liquid crystal display element can have a short response time and great power saving performance.
• COMPOUND, LIQUID-CRYSTAL COMPOSITION, AND RADIOFREQUENCY PHASE SHIFTER
  申请人：DIC Corporation

  公开号：US20220025264A1

  公开（公告）日：2022-01-27

  A compound is represented by general formula (I), a liquid-crystal composition contains this compound, and devices are made using this liquid-crystal composition. Having a large refractive-index anisotropy Δn and a sufficiently high Tni, highly compatible with liquid-crystal compositions, and exhibiting a high dielectric anisotropy in the radiofrequency range, the compound is a useful material for RF phase shifters, phased-array antennae, image recognition devices, distance meters, liquid-crystal displays, liquid-crystal lenses, and birefringent lenses for 3D image display, among other devices.

表征谱图