2,5-Dimethyl-1,8-naphthyridin | 14759-23-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2,5-Dimethyl-1,8-naphthyridin
• 英文别名: 1,8-Naphthyridine, 2,5-dimethyl-；2,5-dimethyl-1,8-naphthyridine
• CAS: 14759-23-0
• 化学式: C₁₀H₁₀N₂
• mdl: MFCD18802770
• 分子量: 158.203
• InChiKey: NLRPBOXEDMQPPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

反应信息

• 作为反应物：
  描述：

  2,5-Dimethyl-1,8-naphthyridin 、 间硝基苯甲醛 生成 2-methyl-5-[(E)-2-(3-nitrophenyl)ethenyl]-1,8-naphthyridine
  参考文献：
  名称：

  SINHA D. R.; LAL A. B., J. INDIAN CHEM. SOC., 1979, 56, NO 2, 164-167

  摘要：

  DOI：

文献信息

• PHOTOSENSITIVE PORPHYRIN DYES FOR DYE-SENSITIZED SOLAR CELLS
  申请人：NATIONAL CHUNG HSING UNIVERSITY

  公开号：US20160005546A1

  公开（公告）日：2016-01-07

  A photosensitive porphyrin-based dye is adapted to be used in a photoelectric converting device such as a dye-sensitized solar cell. The photosensitive porphyrin-based dye has a porphyrin center, at least one electron donor unit, at least one electron acceptor unit and an optional blocker unit wherein the units are directly connected to the porphyrin center or connected to the porphyrin center via ethynyl-bridges.

  一种基于光敏卟啉的染料被改进以在光电转换装置中使用，比如染料敏化太阳能电池。这种基于光敏卟啉的染料具有一个卟啉中心，至少一个电子给体单元，至少一个电子受体单元和一个可选的阻塞单元，其中这些单元直接连接到卟啉中心或通过乙炔桥连接到卟啉中心。
• [EN] CYCLIC COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF<br/>[FR] COMPOSÉ CYCLIQUE AYANT UNE ACTIVITÉ ANTITUMORALE ET SON UTILISATION<br/>[ZH] 一种具有抗肿瘤活性的并环类化合物及其用途
  申请人：INNOVSTONE THERAPEUTICS LTD

  公开号：WO2021254493A1

  公开（公告）日：2021-12-23

  提供了一种作为PRMT5抑制剂的具有全新结构的化合物、其化合物的制备方法及其治疗由PRMT5抑制剂介导的疾病方面的用途。实验证实这些化合物对PRMT5酶都具有较强的抑制作用。还提供了化合物的合成方法，其工艺简单，操作便捷，利于规模化工业生产和应用。
• Process for preparing polyphenylenethers
  申请人：Montedison S.p.A.

  公开号：EP0161164A1

  公开（公告）日：1985-11-13

  Polyphenylenethers are prepared by oxidative polymerization of phenols in the presence of oxygen and of organic bases (amines, by using copper-based catalysts having general formula:where B is a naphthiridine group, with the two nitrogen atoms placed one with respect to the other in any possible relative positions, also substituted by one or more groups such as, e.g., alkyl, cycloalkyl, arylalkyl, aromatic groups, even substituted, containing from 1 to 10 carbon atoms, alkoxy, phenoxy, haloid, dialkylaminic, carboxyl, ketonic, alkoxycarbonyl groups, nitrogroups, amidic groups, etc.; X halogen, or nitro group or perchlorate group, Y bridge compound between the copper atoms, of the pyrazole or imidazole type, z = 0, or 1, wherefore: when z = 0, a and n, either like or unlike each other, are 1 or 2; b = an integer from 1 to 3, extremes included while, when z = 1, n = a = 2 b = 3.

  聚苯醚是在氧气和有机碱（胺）的存在下，使用铜基催化剂通过氧化聚合法制备的，其通式如下： 式中 B 是萘甲脒基团，两个氮原子在任何可能的相对位置上一一对应，也被一个或 多个基团取代，例如烷基、环烷基、芳烷基、芳香基团（即使是取代的），含 1 至 10 个碳原子、烷氧基、苯氧基、卤素、二烷基氨基、羧基、酮基、烷氧基羰基、硝基、酰胺基等； X 卤素、或硝基、或高氯酸盐基团、 Y 铜原子间的桥式化合物，属于吡唑或咪唑类、 z = 0 或 1，因此：当 z = 0 时、 a和n，无论是否相同，均为1或2； 当 z = 1 时，b = 1 至 3 的整数，包括极值、 n = a = 2 b = 3.
• ORGANIC LIGHT-EMITTING DEVICE
  申请人：Samsung Display Co., Ltd.

  公开号：US20160351817A1

  公开（公告）日：2016-12-01

  An organic light-emitting device including a first electrode, a second electrode, and an organic layer between the first electrode and the second electrode and including an emission layer. The organic layer may include a first compound represented by Formula 1 and a second compound represented by Formula 2: When the first compound represented by Formula 1 and the second compound represented by Formula 2 are included in the emission layer, the organic light-emitting device may have improved (e.g. increased) efficiency and lifespan characteristics.
• US4639506A
  申请人：——

  公开号：US4639506A

  公开（公告）日：1987-01-27

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