5-(3-pyridyl)benzo[b]thiophene-2-carboxylic acid | 907945-26-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 5-(3-pyridyl)benzo[b]thiophene-2-carboxylic acid
• 英文别名: 5-(pyridin-3-yl)-1-benzothiophene-2-carboxylic acid；5-pyridin-3-yl-1-benzothiophene-2-carboxylic acid
• CAS: 907945-26-0
• 化学式: C₁₄H₉NO₂S
• 分子量: 255.297
• InChiKey: VWQDDXSFIOKIFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  78.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  methyl 5-(3-pyridyl)benzo[b]thiophene-2-carboxylate 在 lithium hydroxide monohydrate 作用下， 以 甲醇 、 水 为溶剂， 反应 2.0h， 以395 mg的产率得到5-(3-pyridyl)benzo[b]thiophene-2-carboxylic acid
  参考文献：
  名称：

  EP2926660

  摘要：

  公开号：

文献信息

• METHOD FOR PROMOTING PLANT GROWTH
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20150289506A1

  公开（公告）日：2015-10-15

  The present invention provides a method for promoting plant growth, which comprises treating a plant with at least one compound selected from a group consisting of a compound represented by the following Formula (1): and an agriculturally acceptable salt thereof, provided that a method for promoting plant growth which comprises treating plants with a compound corresponding to any one of the following (1) to (5) and an agriculturally acceptable salt thereof is excluded: (1) 4-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (2) 5-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (3) 6-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (4) 7-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, and (5) Benzo[b]thiophene-2-carboxylic acid.

  本发明提供了一种促进植物生长的方法，包括将植物处理至少一种化合物，所述化合物选自以下公式（1）表示的化合物组中的至少一种：以及其农业上可接受的盐，但是排除了使用与以下任一化合物（1）至（5）及其农业上可接受的盐相对应的化合物来促进植物生长的方法：（1）4-（三氟甲基）苯并[b]噻吩-2-羧酸，（2）5-（三氟甲基）苯并[b]噻吩-2-羧酸，（3）6-（三氟甲基）苯并[b]噻吩-2-羧酸，（4）7-（三氟甲基）苯并[b]噻吩-2-羧酸和（5）苯并[b]噻吩-2-羧酸。
• AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP1849465A1

  公开（公告）日：2007-10-31

  The present invention provides a GPR receptor function regulator comprising the compound represented by the formula: [wherein ring A is an optionally substituted isocyclic or heterocyclic ring, P is a bond or spacer, ring D is an optionally substituted monocyclic aromatic ring which may be condensed with a 5-to 7-membered ring, V is a bond or the group represented by the formula -CR14=CR15 - or - N=CR16- (wherein R14, R15 and R16 each represents a hydrogen atom or optionally substituted hydrocarbon group), Q is a bond or spacer, and W is a carboxyl or a group biologically equivalent to a carboxyl] or its salt or a prodrug thereof

  本发明提供了一种 GPR 受体功能调节剂，包括由式表示的化合物： [其中环A是任选取代的异环或杂环，P是键或间隔物，环D是任选取代的单环芳香环，可与5-7元环缩合，V是键或由式-CR14＝CR15-或-N＝CR16-代表的基团（其中R14、R15 和 R16 各代表一个氢原子或任选取代的烃基），Q 是键或间隔物，W 是羧基或生物等价于羧基的基团]或其盐或其原药
• EP1849465
  申请人：——

  公开号：——

  公开（公告）日：——
• Regulating Agent of GPR34 Receptor Function
  申请人：Itoh Fumio

  公开号：US20100130737A1

  公开（公告）日：2010-05-27

  The present invention provides a GPR receptor function regulator comprising the compound represented by the formula: [wherein ring A is an optionally substituted isocyclic or heterocyclic ring, P is a bond or spacer, ring D is an optionally substituted monocyclic aromatic ring which may be condensed with a 5- to 7-membered ring, V is a bond or the group represented by the formula —CR 14 ═CR 15 — or —N═CR 16 — (wherein R 14 , R 15 and R 16 each represents a hydrogen atom or optionally substituted hydrocarbon group), Q is a bond or spacer, and W is a carboxyl or a group biologically equivalent to a carboxyl] or its salt or a prodrug thereof.
• US9955689B2
  申请人：——

  公开号：US9955689B2

  公开（公告）日：2018-05-01