N-methyl-N-sulphopropylaniline | 40567-66-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-methyl-N-sulphopropylaniline
• 英文别名: 3-[methyl(phenyl)azaniumyl]propane-1-sulfonate
• CAS: 40567-66-6
• 化学式: C₁₀H₁₅NO₃S
• mdl: MFCD00087107
• 分子量: 229.3
• InChiKey: NFYWNYJNLDNABX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  66
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N-methyl-N-sulphopropylaniline 、 5-Aminonaphthalene-1-acetic acid 在 sodium nitrite 作用下， 生成 5-(4¹-N-methyl-N-sulphopropylaminophenylazo)-1-naphthaleneacetic acid
  参考文献：
  名称：

  取代的5-苯基偶氮-和5-苯乙烯基-1-萘乙酸的合成及生长素活性

  摘要：

  摘要 合成了植物生长素 1-萘乙酸的两种 5-苯基偶氮衍生物和两种 5-苯乙烯基衍生物作为潜在的受体探针。在标准伸长率测试中，只有苯基偶氮化合物显示出可观的生长素活性。分子模型表明，这种活动可能与采用平面构象的能力有关。

  DOI：

  10.1016/s0031-9422(00)95132-x
• 作为产物：
  描述：

  1,3-丙烷磺内酯 、 N-甲基苯胺 以80%的产率得到
  参考文献：
  名称：

  ZIUMANIS A. X.; ZILNIETSE I. G.; UZIJS X. B., LATVRSR ZINATNU AKAD. VESTIS. KIM. SER., IZV. AN LATVSSR. CEP. XIM., 1979+

  摘要：

  DOI：

文献信息

• Determination method of biological component and reagent kit used therefor
  申请人：——

  公开号：US20020119507A1

  公开（公告）日：2002-08-29

  The present invention provides novel glutathione-dependent formaldehyde dehydrogenase that makes possible quantitative measurement of formaldehyde by cycling reaction, and a determination method of formaldehyde and biological components, such as creatinine, creatine, homocysteine and the like, which produces formaldehyde as a reaction intermediate. In addition, the present invention provides a reagent kit for the above-mentioned determination method. The present invention provides a novel determination method of a homocysteine using transferase utilizing homocysteine and other compound as a pair of substrates. Particularly, the present invention provides a determination method of homocysteine which includes bringing betaine-homocysteine methyltransferase and dimethylglycine oxidase into contact with a sample and measuring produced hydrogen peroxide or formaldehyde. Moreover, the present invention provides novel dimethylglycine oxidase stable to thiol compound, which is suitably used for the measurement. The present invention provides a reagent kit used for any of the above-mentioned determination methods of homocysteines.

  本发明提供了一种新型的谷胱甘肽依赖性甲醛脱氢酶，它使得通过循环反应定量测量甲醛成为可能，并提供了一种测定甲醛和生物成分（如肌酐、肌酸、同型半胱氨酸等）的方法，该方法产生甲醛作为反应中间体。此外，本发明还提供了用于上述测定方法的试剂盒。本发明提供了一种新型的利用同型半胱氨酸和其他化合物作为一对底物的转移酶测定同型半胱氨酸的方法。特别是，本发明提供了一种同型半胱氨酸的测定方法，其中包括将甜菜碱-同型半胱氨酸甲基转移酶和二甲基甘氨酸氧化酶与样品接触，并测量产生的过氧化氢或甲醛。此外，本发明还提供了一种对巯基化合物稳定的新型二甲基甘氨酸氧化酶，适用于测量。本发明提供了用于上述同型半胱氨酸测定方法的试剂盒。
• Multizone element and method for analysis of whole blood
  申请人：EASTMAN KODAK COMPANY (a New Jersey corporation)

  公开号：EP0140337A2

  公开（公告）日：1985-05-08

  A multizone element and method are designed for use for the determination of an analyte in whole blood. In particular, this element and method is useful for the quantitative determination of peroxide-generating analytes, such as glucose or cholesterol, in whole blood. The multizone element has a support having thereon, in order and in fluid contact, a registration zone and a reagent/spreading zone but excludes a whole blood cell filter zone. The reagent/spreading zone has a void volume and average pore size effective to accomodate whole blood, and contains an interactive composition necessary for the analysis. Such composition is capable of providing, upon interaction with the analyte, a dye which can be spectrophotometrically detected at a wavelength greater than or equal to 600 nm.

  一种多区元件和方法设计用于测定全血中的被分析物。 特别是，这种元件和方法可用于定量测定全血中产生过氧化物的被分析物，如葡萄糖或胆固醇。 多区元件有一个支撑物，其上依次有一个登记区和一个试剂/扩散区，但不包括一个全血细胞过滤区。 试剂/扩散区的空隙体积和平均孔径可有效容纳全血，并含有分析所需的交互组合物。 这种组合物在与被分析物交互作用时能够提供一种染料，该染料可在大于或等于 600 纳米的波长下进行分光光度检测。
• Test devices for determination of occult blood and glucose
  申请人：MILES INC.

  公开号：EP0316762A1

  公开（公告）日：1989-05-24

  Test device is useful for determining glucose or occult blood comprising a carrier matrix, glucose oxidase, an indicator system and a glucose derivative that upon addition of water hydrolizes to produce glucose.

  测试装置可用于测定葡萄糖或隐血，包括载体基质、葡萄糖氧化酶、指示系统和葡萄糖衍生物，该衍生物在加水后水解生成葡萄糖。
• Method and kit for the determination of a biological component
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP1213358A2

  公开（公告）日：2002-06-12

  The present invention provides novel glutathione-dependent formaldehyde dehydrogenase that makes possible quantitative measurement of formaldehyde by cycling reaction, and a determination method of formaldehyde and biological components, such as creatinine, creatine, homocysteine and the like, which produces formaldehyde as a reaction intermediate. In addition, the present invention provides a reagent kit for the above-mentioned determination method. The present invention provides a novel determination method of a homocysteine using transferase utilizing homocysteine and other compound as a pair of substrates. Particularly, the present invention provides a determination method of homocysteine which includes bringing betaine-homocysteine methyltransferase and dimethylglycine oxidase into contact with a sample and measuring produced hydrogen peroxide or formaldehyde. Moreover, the present invention provides novel dimethylglycine oxidase stable to thiol compound, which is suitably used for the measurement. The present invention provides a reagent kit used for any of the above-mentioned determination methods of homocysteines.

  本发明提供了新型谷胱甘肽依赖性甲醛脱氢酶，可通过循环反应定量测定甲醛，还提供了一种甲醛和生物成分（如肌酐、肌酸、同型半胱氨酸等）的测定方法，该方法会产生甲醛作为反应中间体。此外，本发明还提供了用于上述测定方法的试剂盒。本发明提供了一种利用转移酶测定同型半胱氨酸的新型方法，该方法利用同型半胱氨酸和其他化合物作为一对底物。特别是，本发明提供了一种同型半胱氨酸的测定方法，包括使甜菜碱-同型半胱氨酸甲基转移酶和二甲基甘氨酸氧化酶与样品接触，并测定产生的过氧化氢或甲醛。此外，本发明还提供了对硫醇化合物稳定的新型二甲基甘氨酸氧化酶，适合用于测量。本发明提供了一种试剂盒，可用于上述任何同型半胱氨酸的测定方法。
• ZIUMANIS A. X.; ZILNIETSE I. G.; UZIJS X. B., LATVRSR ZINATNU AKAD. VESTIS. KIM. SER., IZV. AN LATVSSR. CEP. XIM., 1979+
  作者：ZIUMANIS A. X.、 ZILNIETSE I. G.、 UZIJS X. B.

  DOI：——

  日期：——