1-(2-Hydroxyphenyl)-2-(4-hydroxyphenyl)ethan | 1875-21-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 1-(2-Hydroxyphenyl)-2-(4-hydroxyphenyl)ethan
• 英文别名: 2,4'-Dihydroxy-bibenzyl；bibenzyl-2,4'-diol；4-[2(Hydroxyphenyl)-ethyl]phenol；2-[2-(4-hydroxyphenyl)ethyl]phenol
• CAS: 1875-21-4
• 化学式: C₁₄H₁₄O₂
• 分子量: 214.264
• InChiKey: KNTILYAOZSPWRL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  邻甲氧基苯乙酰氯 在 三氯化铝 、 氢溴酸 、 溶剂黄146 、 肼 作用下， 反应 2.0h， 生成 1-(2-Hydroxyphenyl)-2-(4-hydroxyphenyl)ethan
  参考文献：
  名称：

  Carpenter; Hunter, Journal of Applied Chemistry, 1951, vol. 1, p. 217,223

  摘要：

  DOI：

文献信息

• Synthesis and evaluation of inhibitory activity <i>in vitro</i> of dihydrostilbenes against human neutrophil elastases
  作者：Guo-Li Huang、Bo Liu、Xing-Jun Tian、Ye-Gao Chen

  DOI：10.1080/10286020.2019.1571489

  日期：2020.4.2

  Twelve dihydrostilbenes (including five new analogues) were prepared by the Witting-Hornor reaction from appropriate aromatic aldehydes and phosphonate esters, followed by hydrogenation in five steps. The in vitro inhibition activity against human neutrophil elastase (HNE) of these dihydrostilbenes was evaluated, and three 1,2-dihydroxylated dihydrostilbenes (6b, 6j, and 6l) exhibited stronger inhibitory

  通过Witting-Hornor反应，由适当的芳族醛和膦酸酯制备十二种二氢苯乙烯（包括五个新的类似物），然后分五个步骤进行氢化。评估了这些二氢芪酯对人中性粒细胞弹性蛋白酶（HNE）的体外抑制活性，并且三个1,2-二羟基化二氢芪酯（6b，6j和6l）对HNE的抑制活性比其他类似物强。
• Electrophotographic photoreceptor
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP1286224A1

  公开（公告）日：2003-02-26

  An electrophotographic photoreceptor, comprising a photosensitive layer formed on an electroconductive substrate, wherein the photosensitive layer comprises a resin having repeating units of the following formula (1): where, in the formula (1), A represents a plurality of bivalent groups including at least two members selected from the group consisting of bivalent groups of the following formulae (2), (3) and (4): where, in the formulae (2), (3) and (4), each of R1 to R24 which are independent of one another, represents a hydrogen atom, a substituted or unsubstituted C1-10 alkyl group, a substituted or unsubstituted C1-10 alkoxyl group, a halogen atom, a halogenated alkyl group or a substituted or unsubstituted C6-20 aromatic group, and each of X1, X2 and X3 which may be the same or different, represents a single bond, a bivalent organic group of the formula (5), -O-, -S-, -CO-, -SO2- or -(CH2)s- (wherein S is an integer of from 2 to 5): where, in the formula (5), each of R25 to R29 which are independent of one another, represents a hydrogen atom, a substituted or unsubstituted C1-10 alkyl group, a substituted or unsubstituted C1-10 alkoxyl group, a halogen atom, a halogenated alkyl group or a substituted or unsubstituted C6-20 aromatic group, provided that R25 and R26, and R27 and R28, may be bonded to each other to form a cycle, t is an integer of from 0 to 5, R29 is a C1-10 alkyl group, a C1-10 alkoxyl group, a halogen atom, a halogenated alkyl group or a substituted or unsubstituted C6-20 aromatic group, and u is an integer of from 0 to 4.

  一种电子照相感光器，包括在导电基底上形成的感光层，其中感光层包括具有下式(1)重复单元的树脂： 其中，在式 (1) 中，A 代表多个二价基团，包括至少两个从下式 (2)、(3) 和 (4) 的二价基团组成的组中选出的成员： 其中，在式(2)、(3)和(4)中，彼此独立的 R1 至 R24 各自代表氢原子、取代或未取代的 C1-10 烷基、取代或未取代的 C1-10 烷氧基、卤素原子、卤代烷基或取代或未取代的 C6-20 芳基，且 X1、X2 和 X3 可相同或不同，各自代表单键、式(5)的二价有机基团、 -O-、-S-、-CO-、-SO2- 或-(CH2)s-（其中 S 为 2 至 5 的整数）： 其中，在式 (5) 中，相互独立的 R25 至 R29 分别代表氢原子、取代或未取代的 C1-10 烷基、取代或未取代的 C1-10 烷氧基、卤素原子、卤代烷基或取代或未取代的 C6-20 芳基、t为 0 至 5 的整数，R29 为 C1-10 烷基、C1-10 烷氧基、卤素原子、卤代烷基或取代或未取代的 C6-20 芳基，u 为 0 至 4 的整数。
• CURABLE COMPOSITION AND CURED ARTICLE
  申请人：Adeka Corporation

  公开号：EP2749581A1

  公开（公告）日：2014-07-02

  Provided are: a curable composition from which a cured article having excellent molding processability and high heat resistance as well as such a high Tg that it can be used as a molding resin for a SiC power semiconductor can be obtained; and a cured article thereof. The curable composition comprises: 100 parts by mass of a compound having at least two partial structures represented by the following Formula (1) in the molecule as a component (A); 0.5 to 3 parts by mass of a thermal radical generator as a component (B); and 0 to 50 parts by mass of other radical-reactive compound as a component (C): (wherein, ring A represents a benzene ring or a cyclohexyl ring; R1 represents an alkylene group having 1 to 6 carbon atoms; R2 represents an alkyl group having 1 to 4 carbon atoms; a represents a number of 0 or 1; b represents an integer of 0 to 3; and c represents a number of 1 or 2).

  本发明提供了：一种可固化组合物，通过该组合物可以获得一种固化物，该固化物具有优异的成型加工性和高耐热性，并且具有很高的 Tg，可以用作碳化硅功率半导体的成型树脂；以及一种固化物。固化组合物包括100 份（质量）分子中至少有两个部分结构由下式 (1) 表示的化合物作为组分 (A)； 0.5 至 3 份（质量）热自由基发生器作为组分 (B)；以及 0 至 50 份（质量）其他自由基反应化合物作为组分 (C)： (其中，环 A 代表苯环或环己基环；R1 代表具有 1 至 6 个碳原子的亚烷基；R2 代表具有 1 至 4 个碳原子的烷基；a 代表 0 或 1；b 代表 0 至 3 的整数；c 代表 1 或 2）。
• 654. Photochemical transformations. Part XIX. Some photosensitive protecting groups
  作者：D. H. R. Barton、Y. L. Chow、A. Cox、G. W. Kirby

  DOI：10.1039/jr9650003571

  日期：——
• SERIES OF SKIN-WHITENING (LIGHTENING) COMPOUNDS
  申请人：Unigen, Inc.

  公开号：EP2323612B1

  公开（公告）日：2019-07-10