2-(2-hydroxyethyl)-3a,4,5,6,7,7a-hexahydro-4,7-epoxyisoindole-1,3-dione | 91877-89-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-(2-hydroxyethyl)-3a,4,5,6,7,7a-hexahydro-4,7-epoxyisoindole-1,3-dione
• CAS: 91877-89-3
• 化学式: C₁₀H₁₃NO₄
• 分子量: 211.21
• InChiKey: QQXHRXWQSQDDDA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  66.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] BIO-RELATED SUBSTANCE MODIFIED BY MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE<br/>[FR] SUBSTANCE D'ORIGINE BIOLOGIQUE MODIFIÉE PAR UN DÉRIVÉ DU POLYÉTHYLÈNEGLYCOL MULTIFONCTIONNALISÉ<br/>[ZH] 一种多官能化聚乙二醇衍生物修饰的生物相关物质
  申请人：XIAMEN SINOPEG BIOTECH CO LTD

  公开号：WO2016050208A1

  公开（公告）日：2016-04-07

  本发明公开一种多官能化聚乙二醇衍生物（式1）修饰的生物相关物质。其具有H型结构，包括一个线性主轴LPEG及四个PEG分支链，n1、n2、n3、n4分别为分支链的聚合度；U1、U2为连接LPEG和两个PEG分支链的三价支化基团；F1、F2含有功能性基团或其被保护形式R01，且R01的个数为1个或多个。分子中任一个连接基或其与相邻杂原子基团形成的连接基可稳定存在或可降解；分子中任一个PEG链段各自独立地为多分散性或单分散性。1个H型分子可修饰多种或多个生物相关物质，修饰产物支化结构灵活，具有高载药量、可优化的药代动力学和组织分布情况，还可携带2种不同功能的生物相关物质，产生荧光性质或靶向功能。
• POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME
  申请人：Zheng Shiying

  公开号：US20130047844A1

  公开（公告）日：2013-02-28

  A method for preparing a polymeric material includes: providing a polymeric matrix having at least one polymer and at least one porogen; and degrading the at least one porogen at a temperature T≦1.1 T g , where T g is a glass transition temperature of the polymeric matrix. The degrading step includes exposing the polymeric matrix to thermal degradation, chemical degradation, electrical degradation and/or radiation degradation, wherein the polymeric material has a permeability at least 1.2 times a permeability of the polymeric matrix for a gas, and a selectivity of the polymeric material is at least 0.35 times a selectivity of the polymeric matrix for a gas pair. The method preferably provides gas separation membranes that exceed Robeson's upper bound relationship for at least one gas separation pair. Novel polymeric materials, gas separation membranes and fluid component separation methods are also described.
• [EN] POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME<br/>[FR] POLYMÈRES, MEMBRANES POLYMÈRES ET LEURS PROCÉDÉS DE FABRICATION
  申请人：AIR PROD & CHEM

  公开号：WO2011143530A1

  公开（公告）日：2011-11-17

  A method for preparing a polymeric material includes: providing a polymeric matrix having at least one polymer and at least one porogen; and degrading the at least one porogen at a temperature T ≤ 1.1 Tg, where Tg is a glass transition temperature of the polymeric matrix. The degrading step includes exposing the polymeric matrix to thermal degradation, chemical degradation, electrical degradation and/or radiation degradation, wherein the polymeric material has a permeability at least 1.2 times a permeability of the polymeric matrix for a gas, and a selectivity of the polymeric material is at least 0.35 times a selectivity of the polymeric matrix for a gas pair. The method preferably provides gas separation membranes that exceed Robeson's upper bound relationship for at least one gas separation pair. Novel polymeric materials, gas separation membranes and fluid component separation methods are also described.