2-[2-(Dibenzylamino)ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one | 1236996-20-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2-[2-(Dibenzylamino)ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one
• 英文别名: 2-[2-(dibenzylamino)ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one
• CAS: 1236996-20-5
• 化学式: C₄₄H₄₈N₄O₂
• 分子量: 664.891
• InChiKey: KWPIUQKWBRIHOF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  50
• 可旋转键数：
  13
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  39.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  罗丹明B乙二胺 、 溴甲苯 在 potassium carbonate 作用下， 以 氯仿 为溶剂， 以54%的产率得到2-[2-(Dibenzylamino)ethyl]-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one
  参考文献：
  名称：

  New fluorescent and colorimetric chemosensors based on the rhodamine and boronic acid groups for the detection of Hg2+

  摘要：

  Novel rhodamine B (RB) derivatives bearing mono and bis-boronic acid groups were investigated as Hg2+ selective fluorescent and colorimetric sensors. These derivatives are first examples of reversible fluorescent chemosensors for Hg2+ which utilized boronic acid groups as binding sites. Two new RB-boronic acid derivatives displayed selective 'Off-On'-type fluorescent enhancements and distinct color changes with Hg2+. Selective fluorescent enhancement of two rhodamine derivatives was attributed to ring opening from the spirolactam (nonfluorescent) to ring-opened amide (fluorescent). (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.04.067

文献信息

• New fluorescent and colorimetric chemosensors based on the rhodamine and boronic acid groups for the detection of Hg2+
  作者：Sook Kyung Kim、K.M.K. Swamy、So-Young Chung、Ha Na Kim、Min Jung Kim、Yongsuk Jeong、Juyoung Yoon

  DOI：10.1016/j.tetlet.2010.04.067

  日期：2010.6

  Novel rhodamine B (RB) derivatives bearing mono and bis-boronic acid groups were investigated as Hg2+ selective fluorescent and colorimetric sensors. These derivatives are first examples of reversible fluorescent chemosensors for Hg2+ which utilized boronic acid groups as binding sites. Two new RB-boronic acid derivatives displayed selective 'Off-On'-type fluorescent enhancements and distinct color changes with Hg2+. Selective fluorescent enhancement of two rhodamine derivatives was attributed to ring opening from the spirolactam (nonfluorescent) to ring-opened amide (fluorescent). (C) 2010 Elsevier Ltd. All rights reserved.