2,6-dicyano-5-methyl-3-(2-naphthyl)aniline | 1234872-96-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,6-dicyano-5-methyl-3-(2-naphthyl)aniline
• 英文别名: 2-Amino-4-methyl-6-naphthalen-2-ylbenzene-1,3-dicarbonitrile；2-amino-4-methyl-6-naphthalen-2-ylbenzene-1,3-dicarbonitrile
• CAS: 1234872-96-8
• 化学式: C₁₉H₁₃N₃
• 分子量: 283.332
• InChiKey: CIKIQPOWLYFVRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  73.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-(2-nitrovinyl)naphthalene 、 丙二腈 在 sodium carbonate 作用下， 以 乙醇 为溶剂， 反应 4.0h， 以84%的产率得到2,6-dicyano-5-methyl-3-(2-naphthyl)aniline
  参考文献：
  名称：

  A Novel Synthesis of 3-Aryl-2,6-dicyano-5-methylanilines via Reaction between Nitrostyrenes and Malononitrile

  摘要：

  A novel and simple synthesis of 3-aryl-2,6-dicyano-5-methylanilines is described. Reactions between nitrostyrenes and excess malononitrile in the presence of sodium carbonate in 80% ethanol proceeded at room temperature to afford the aromatic products in good yields. A mechanism for the formation of the products is proposed.

  DOI：

  10.1055/s-0029-1218717

文献信息

• A Novel Synthesis of 3-Aryl-2,6-dicyano-5-methylanilines via Reaction between Nitrostyrenes and Malononitrile
  作者：Mehdi Adib、Bagher Mohammadi、Samira Ansari、Hamid Bijanzadeh、Long-Guan Zhu

  DOI：10.1055/s-0029-1218717

  日期：2010.5

  A novel and simple synthesis of 3-aryl-2,6-dicyano-5-methylanilines is described. Reactions between nitrostyrenes and excess malononitrile in the presence of sodium carbonate in 80% ethanol proceeded at room temperature to afford the aromatic products in good yields. A mechanism for the formation of the products is proposed.