N,N-二甲基-N-(2-羟基乙基)十六烷基季铵磷酸盐 | 85563-48-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N,N-二甲基-N-(2-羟基乙基)十六烷基季铵磷酸盐
• 中文别名: 羟乙基鲸蜡基二甲基磷酸胺
• 英文名称: Hexadecyl(2-hydroxyethyl)dimethylammonium dihydrogen phosphate
• 英文别名: dihydrogen phosphate;hexadecyl-(2-hydroxyethyl)-dimethylazanium
• CAS: 85563-48-0
• 化学式: C20H46NO5P
• 分子量: 411.6
• InChiKey: SGZVXLFVBKDMJH-UHFFFAOYSA-M

物化性质

• 密度：
  1.07[at 20℃]
• 闪点：
  100℃
• LogP：
  1.590 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  3.98
• 重原子数：
  27
• 可旋转键数：
  17
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  101
• 氢给体数：
  3
• 氢受体数：
  5

安全信息

• 危险品标志：
  N,Xi
• 危险类别码：
  R36/38,R51/53
• 危险品运输编号：
  UN 3082 9/PG 3
• 安全说明：
  S26,S61

文献信息

• USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND AGENTS CONTAINING SUCH ACTIVE INGREDIENTS
  申请人：Subkowski Thomas

  公开号：US20120263659A1

  公开（公告）日：2012-10-18

  The invention relates to a TRPM8 modulator for achieving a cooling effect on the skin or a mucous membrane.

  这项发明涉及一种TRPM8调节剂，用于在皮肤或粘膜上产生降温效果。
• Catalytic Hydrogenation for Producing Amines from Carboxylic Acid Amides, Carboxylic Acid Diamides, Di-, Tri-, or Polypeptides, or Peptide Amides
  申请人：Evonik Degussa GmbH

  公开号：US20160272571A1

  公开（公告）日：2016-09-22

  The present invention relates to a process for the preparation of amines, comprising the following steps: a. reaction of a (i) carboxylic acid amide of the general formula (I), or (ii) carboxylic acid diamide of the general formula (II), or (iii) di-, tri- or polypeptide, or (iv) peptide amide with carboxy-terminal amide function with an alkylating agent, b. addition of a hydrogenation catalyst to the reaction mixture in a molar ratio of from 1:10 to 1:100 000, based on carboxylic acid amide, carboxylic acid diamide, di-, tri- or polypeptide or peptide amide, c. reaction of the reaction mixture with hydrogen, where a hydrogen pressure of from 0.1 bar to 200 bar is established and where a temperature in a range of from 0° C. to 250° C. is established.

  本发明涉及一种氨基的制备方法，包括以下步骤：a. 将通式（I）的羧酸酰胺，或通式（II）的羧酸二酰胺，或二肽、三肽或多肽，或带有羧基末端酰胺功能的肽酰胺与烷基化剂发生反应，b. 在摩尔比为1:10至1:100,000的范围内向反应混合物中加入氢化催化剂，基于羧酸酰胺、羧酸二酰胺、二肽、三肽或多肽或肽酰胺，c. 将反应混合物与氢气反应，在此建立氢气压力为0.1巴至200巴，并在0°C至250°C的温度范围内进行反应。
• USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS
  申请人：BASF SE

  公开号：US20200190052A1

  公开（公告）日：2020-06-18

  The invention relates primarily to a method of modulation, preferably of in vitro and/or in vivo modulation, of the cold menthol receptor TRPM8, wherein the receptor is contacted with at least one modulator selected from the group consisting of the compounds of the structure type 1 described herein. The present invention further relates to corresponding uses and compositions comprising such compounds.

  该发明主要涉及一种调制方法，优选是体外和/或体内调制寒冷薄荷醇受体TRPM8的方法，其中受体与本文描述的结构类型1的化合物群中至少一种调制剂接触。本发明还涉及相关用途和包含这些化合物的组合物。
• [EN] PD ON CERIA CATALYTIC SYSTEM FOR SELECTIVE HYDROGENATIONS OF TRIPLE BONDS<br/>[FR] SYSTÈME CATALYTIQUE PD SUR CÉRIUM POUR HYDROGÉNATIONS SÉLECTIVES DE TRIPLES LIAISONS
  申请人：DSM IP ASSETS BV

  公开号：WO2015044410A1

  公开（公告）日：2015-04-02

  The present invention relates to a new catalytic system, furthermore it relates to processes of producing such catalytic systems as well as their use in selective hydrogenations of C-C triple bonds to C-C double bonds.

  本发明涉及一种新的催化系统，此外还涉及生产这种催化系统的过程以及它们在选择性氢化C-C三键至C-C双键中的应用。
• [EN] PD ON BOEHMITE CATALYTIC SYSTEM FOR SELECTIVE HYDROGENATION OF TRIPLE BONDS<br/>[FR] SYSTÈME CATALYTIQUE PD SUR BŒHMITE POUR HYDROGÉNATIONS SÉLECTIVES DE TRIPLES LIAISONS
  申请人：DSM IP ASSETS BV

  公开号：WO2015044411A1

  公开（公告）日：2015-04-02

  The present invention relates to a new catalytic system, furthermore it relates to processes of producing such catalytic systems as well as their use in selective hydrogenations of C-C triple bonds to C-C double bonds.

  本发明涉及一种新的催化系统，此外还涉及生产这种催化系统的过程以及它们在C-C三键选择性加氢到C-C双键中的应用。