N-aminoisoquinolinium perchlorate | 76326-95-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: N-aminoisoquinolinium perchlorate
• 英文别名: 2-Aminoisoquinolinium perchlorate；Isoquinolinium, 2-amino-, perchlorate；isoquinolin-2-ium-2-amine;perchlorate
• CAS: 76326-95-9
• 化学式: C₉H₉N₂*ClO₄
• 分子量: 244.634
• InChiKey: DRHQWEAEJSWUAJ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.91
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  104
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  N-aminoisoquinolinium perchlorate 在 氧气 、 氧化亚氮 作用下， 以 乙腈 为溶剂， 反应 0.08h， 以92%的产率得到isoquinolinium perchlorate
  参考文献：
  名称：

  Radical Scavenging by N -Aminoazaaromatics

  摘要：

  N-Aminoazaaromatics were found to react with nitric oxide in the presence of oxygen to afford deaminated products in high yields. The reaction proceeded almost instantaneously in various solvents including water, and one to two equivalent of NO was consumed depending upon the amount of oxygen coexisted, and 1 equivalent of N2O was released in the reaction. In addition, N-aminoazoles were deaminated by potassium superoxide to give parent azoles in good yields. Two equivalents of superoxide was consumed, and about half equivalents of both nitrite and nitrate ion were released. The results demonstrated that N-aminoazoles have ability to protect the biological system against the oxidation promoted by radicals such as nitrogen oxides and superoxide. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0968-0896(00)00118-8
• 作为产物：
  描述：

  2-aminoisoquinolinium mesitylenesulfonate 在 高氯酸 作用下， 以 乙醇 为溶剂， 生成 N-aminoisoquinolinium perchlorate
  参考文献：
  名称：

  Takeuchi, Hiroshi; Higuchi, Dai; Adachi, Taki, Journal of the Chemical Society. Perkin transactions I, 1991, # 6, p. 1525 - 1529

  摘要：

  DOI：

文献信息

• Radical Scavenging by N -Aminoazaaromatics
  作者：Takashi Itoh、Michiko Miyazaki、Hiromi Maeta、Yûji Matsuya、Kazuhiro Nagata、Akio Ohsawa

  DOI：10.1016/s0968-0896(00)00118-8

  日期：2000.8

  N-Aminoazaaromatics were found to react with nitric oxide in the presence of oxygen to afford deaminated products in high yields. The reaction proceeded almost instantaneously in various solvents including water, and one to two equivalent of NO was consumed depending upon the amount of oxygen coexisted, and 1 equivalent of N2O was released in the reaction. In addition, N-aminoazoles were deaminated by potassium superoxide to give parent azoles in good yields. Two equivalents of superoxide was consumed, and about half equivalents of both nitrite and nitrate ion were released. The results demonstrated that N-aminoazoles have ability to protect the biological system against the oxidation promoted by radicals such as nitrogen oxides and superoxide. (C) 2000 Elsevier Science Ltd. All rights reserved.
• Takeuchi, Hiroshi; Higuchi, Dai; Adachi, Taki, Journal of the Chemical Society. Perkin transactions I, 1991, # 6, p. 1525 - 1529
  作者：Takeuchi, Hiroshi、Higuchi, Dai、Adachi, Taki

  DOI：——

  日期：——