1,3,4,7-Tetramethyl-isoindol | 20944-65-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 1,3,4,7-Tetramethyl-isoindol
• 英文别名: 1,3,4,7-Tetramethyl-2H-isoindole；1,3,4,7-tetramethyl-2H-isoindole
• CAS: 20944-65-4
• 化学式: C₁₂H₁₅N
• 分子量: 173.258
• InChiKey: PDENJZYMZXMITD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  15.8
• 氢给体数：
  1
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,3,4,7-Tetramethyl-isoindol 以 苯 为溶剂， 生成 (1,3,4,7-tetramethyl-1H-isoindol-1-yl)-succinic acid anhydride
  参考文献：
  名称：

  1,3,4,7-四甲基异吲哚的化学性质及通往四苯并卟啉体系的途径

  摘要：

  描述了1,3,4,7-四甲基异吲哚的各种反应。考察了在各种溶剂中具有相应的1 H-异吲哚的互变异构现象。自氧化产生两种化合物，它们被配制成1-羟基-和1-氢过氧-1 H-异吲哚衍生物。亲双烯体的添加很复杂：马来酸酐产生Diels-Alder加合物（IX），随后异构化（熔融或在溶液中）得到（X）。乙炔二甲酸二甲酯可同时产生1：1和1：1的加合物：为这些化合物提出了结构。当与金属粉末或金属盐一起加热时，1,3,4,7-四甲基异吲哚得到金属-八甲基四苯并卟啉。

  DOI：

  10.1039/j39700001251

文献信息

• ISOMERIZATION OF OLEFINIC COMPOUNDS
  申请人：BASF SE

  公开号：US20140051889A1

  公开（公告）日：2014-02-20

  The present invention relates to a process for preparing an olefinically unsaturated phosphonium salt having at least two olefinic double bonds, of which one double bond has a Z or cis conformation and the second or a further double bond an E conformation, from an olefinically unsaturated phosphonium salt having at least two olefinic double bonds of different configuration compared to the target compound, and both especially have an all-E or all-trans conformation. In addition, the invention provides for the use of the compound obtained by the process for provision of terpenoid substances as medicaments.

  本发明涉及一种制备至少具有两个烯丙基双键的烯丙基未饱和膦盐的方法，其中一个双键具有Z或顺式构象，第二个或进一步的双键具有E构象，从至少具有两个与目标化合物不同构象的烯丙基未饱和膦盐中制备。此外，本发明还提供了通过该方法获得的化合物用于作为药物提供萜类物质的用途。
• METHOD FOR SOLID FREEFORM FABRICATION
  申请人：Ricoh Company, Ltd.

  公开号：EP3064340A2

  公开（公告）日：2016-09-07

  The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using 3D printing. A layer of prepolymer is deposited on a build plate to form a powder bed. The deposited powder bed is heated to about 50 °C to about 170 °C. Then, a solution of activating agent is printed on the powder bed in a predetermined pattern, and a stimulus is applied converting the prepolymer to the final polymer. After a predetermined period of time, sequential layers are printed to provide the three-dimensional article. The three-dimensional object can be cured to produce the three-dimensional article composed of the final polymers.

  本发明提供了利用三维打印技术制造聚合物三维物品的方法、工艺和系统。在构建板上沉积一层预聚物以形成粉末床。将沉积的粉末床加热至约 50°C 至约 170°C。然后，将活化剂溶液按预定图案印在粉末床上，并施加刺激，使预聚物转化为最终聚合物。经过一段预定的时间后，印刷出连续的层，形成三维物体。三维物体可以固化，以生产由最终聚合物组成的三维物品。
• Method for solid freeform fabrication
  申请人：Ricoh Company, LTD.

  公开号：US10066119B2

  公开（公告）日：2018-09-04

  The present invention provides methods, processes, and systems for the manufacture of three-dimensional articles made of polymers using 3D printing. A layer of prepolymer is deposited on a build plate to form a powder bed. The deposited powder bed is heated to about 50° C. to about 170° C. Then, a solution of activating agent is printed on the powder bed in a predetermined pattern, and a stimulus is applied converting the prepolymer to the final polymer. After a predetermined period of time, sequential layers are printed to provide the three-dimensional article. The three-dimensional object can be cured to produce the three-dimensional article composed of the final polymers.

  本发明提供了利用三维打印技术制造聚合物三维物品的方法、工艺和系统。在构建板上沉积一层预聚物以形成粉末床。将沉积的粉末床加热至约 50°C 至约 170°C。然后，将活化剂溶液按预定图案印在粉末床上，并施加刺激，将预聚物转化为最终聚合物。经过一段预定的时间后，印刷出连续的层，形成三维物体。三维物体可以固化，以生产由最终聚合物组成的三维物品。
• Preparation of soluble tetrabenzoporphyrins with substituents at the peripheral positions
  作者：Yoko Matsuzawa、Kunihiro Ichimura、Kazuaki Kudo

  DOI：10.1016/s0020-1693(97)06132-x

  日期：1998.8

  The preparation of 1,4,8,11,15,18,22,25-octamethyltetrabenzo[b,g,l,q] porphinatonickel (II) having substituents at the peripheral positions was performed by the cyclotetramerization of a 5-substituted 1,3,4,7-tetramethylisoindole, which was prepared by the condensation of 5-substituted hexane-2,5-dione with 2,5-dimethylpyrrole. It was found that the products consist of mixtures of macrocycles with different numbers of peripheral substituents. This resulted from the ring-opening reaction of 2,5-dimethylpyrrole to form unsubstituted 2,5-hexanedione during the isoindole synthesis, The acidolytic side reaction of the dimethylpyrrole was suppressed by employing hexadecane-7,10-dione so that purified tetrabenzoporphinatonickels with hexyl residues at the 'beta'-position were obtained. The macrocycles thus prepared displayed excellent solubility in organic solvents. (C) 1998 Elsevier Science S.A. All rights reserved.
• Conductive molecular crystals. Structural, electrical, and magnetic properties of partially oxidized octamethyltetrabenzporphyrinatonickel(II)
  作者：Terry E. Phillips、Raymond P. Scaringe、Brian M. Hoffman、James A. Ibers

  DOI：10.1021/ja00530a022

  日期：1980.5