N-(4-羟基苯基)-乙酰胺与3,7-二氢-1,3,7-三甲基-1H-嘌呤-2,6-二酮和5-(2-甲基丙基)-5-(2-丙烯基)-2,4,6(1H,3H,5H)-嘧啶三酮的混合物 | 122018-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 中文名称: N-(4-羟基苯基)-乙酰胺与3,7-二氢-1,3,7-三甲基-1H-嘌呤-2,6-二酮和5-(2-甲基丙基)-5-(2-丙烯基)-2,4,6(1H,3H,5H)-嘧啶三酮的混合物
• 英文名称: Fioricet
• 英文别名: N-(4-hydroxyphenyl)acetamide;5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione;1,3,7-trimethylpurine-2,6-dione
• CAS: 122018-95-5
• 化学式: C27H35N7O7
• 分子量: 569.6
• InChiKey: KJNFMGMNZKFGIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.28
• 重原子数：
  41
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  183
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• SILK RESERVOIRS FOR DRUG DELIVERY
  申请人：Trustees of Tufts College

  公开号：EP2827884A1

  公开（公告）日：2015-01-28
• METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION
  申请人：LeMahieu Edward

  公开号：US20080066741A1

  公开（公告）日：2008-03-20

  Systems and methods for delivery of a drug to the respiratory system of a patient are provided, where the drug is supplied in purified air at a positive pressure relative to atmospheric pressure. With the systems and methods of the present disclosure, medication available in a variety of forms is introduced in a controlled fashion into the purified air stream in aerosol, nebulized, or vaporized form.
• METHOD AND APPARATUS FOR PACKAGING AND DISPENSING PHARMACEUTICALS
  申请人：Tramonte Arturo

  公开号：US20110240504A1

  公开（公告）日：2011-10-06

  A method of packaging one or more pharmaceuticals comprising separating a plurality of unit doses into a plurality of unit dose compartments, wherein each unit dose compartment of the plurality of unit dose compartments holds only one unit dose of the plurality of unit doses, each unit dose having the same strength, wherein the plurality of unit doses is precisely a quantity equal to a most commonly prescribed number of unit doses in individual prescriptions for the unit dose, or a multiple thereof is provided. Also provided are kits prepared by the method. Methods for designing such kits and packaging are also provided.
• [EN] METHODS AND SYSTEMS OF DELIVERING MEDICATION VIA INHALATION<br/>[FR] PROCÉDÉS ET SYSTÈMES D'ADMINISTRATION D'UNE MÉDICATION PAR INHALATION
  申请人：NEXT SAFETY INC

  公开号：WO2008116165A9

  公开（公告）日：2009-06-11

  [EN] Systems and methods for delivery of a drug to the respiratory system of a patient are provided, where the drug is supplied in purified air at a positive pressure relative to atmospheric pressure. With the systems and methods of the present disclosure, medication available in a variety of forms is introduced in a controlled fashion into the purified air stream in aerosol, nebulized, or vaporized form.
  [FR] L'invention concerne des procédés d'administration d'un médicament au système respiratoire d'un patient, où le médicament est fourni dans de l'air purifié à une pression positive par rapport à la pression atmosphérique. Avec les systèmes et procédés de la présente description, une médication disponible sous une variété de formes est introduite de manière contrôlée dans le courant d'air purifié dans un aérosol, sous forme nébulisée ou vaporisée.
• [EN] SILK RESERVOIRS FOR DRUG DELIVERY<br/>[FR] RÉSERVOIRS DE SOIE POUR L'ADMINISTRATION DE MÉDICAMENTS
  申请人：TUFTS COLLEGE

  公开号：WO2013142119A1

  公开（公告）日：2013-09-26

  The present invention is directed to silk-based drug delivery compositions for controlled, sustained delivery of therapeutic agent(s) as well as methods of making and using the same.